Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1980-01-16
1987-03-31
Siegel, Alan
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
2604108, 560263, 514546, A61K 3122, C11C 302, C07C 6702
Patent
active
046543708
ABSTRACT:
Glycerides esterified with one or two moles of valproic acid and optionally esterified with fatty acids at the remaining hydroxy position(s) have been found to have the same useful therapeutic effect as valproic acid alone but without causing gastric irritation.
REFERENCES:
patent: 3686238 (1972-08-01), Zaffaroni
patent: 4423071 (1983-12-01), Chignac et al.
Meijer et al, Clinical and Pharmacological Aspects of Sodium Valproate (Epelim) in the Treatment of Epilepsy, Ed. N. J. Legg, published by McS Consultants, 1975, pp. 70-75.
Keil, Z. Physiol. Chem., 282, pp. 137-142 (1947), (Corresponds to Chem. Abstracts, 43:6164-65.)
Marriott, III Thomas B.
Paris Gerard Y.
Abbott Laboratories
Katz Martin L.
Siegel Alan
Weinstock Steven F.
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