Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-08-21
1999-02-23
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 4352523, 435325, 435410, 43525233, 43525411, 435196, 536 232, 536 235, C12P 2102, C12N 1555, C12N 1563, C12N 100, C12N 610
Patent
active
058742484
ABSTRACT:
The invention provides a human glutathione S-transferase (GSTH) and polynucleotides which identify and encode GSTH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of GSTH.
REFERENCES:
Thier, R. et al., "Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes", Proc. Natl. Acad. Sci. USA, 90: 8576-8580 (1993).
Simula, T.P. et al., "Human glutathione S-transferase-expressing Salmonella typhimurium tester strains to study the activation/detoxification of mutagenic compounds: studies with halogenated compounds, aromatic amines and aflatoxin B.sub.1 ", Carcinogenesis, 14: 1371-1376 (1993).
Dirven, H.A.A.M., et al., "Involvement of Human Glutathione S Transferase Isoenzymes in the Conjugation of Cyclophosphamide Metabolites with Glutathione", Cancer Res., 54: 6215-6220 (1994).
Kodym, R. et al., (Direct Submission), GenBank Sequence Database (Accession U80819), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1750199; GI 1750200) Dec. 23, 1996.
Kodym, R. et al., (Direct Submission), GenBank Sequence Database (Accession U90313), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1899207; GI 1899208) Mar. 21, 1996.
Corley Neil C.
Hillman Jennifer L.
Shah Purvi
Billings Lucy J.
Bugaisky Gabriele E.
Incyte Pharmaceuticals Inc.
Wax Robert A.
LandOfFree
Glutathione S-transferase homolog does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Glutathione S-transferase homolog, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glutathione S-transferase homolog will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-305720