Glutathione peroxidase mimetics and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S001000

Reexamination Certificate

active

07923442

ABSTRACT:
This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidative stress.

REFERENCES:
Malmsten et al. (CAS Accession No. 1971:492788).
Mlochowski et al. (CAS Accession No. 1981:192022).
Nakashima et al. “Optically Active Seleninate Esters: Isolation, Absolute Configuration, Racemization Mechanism, and Transformation into Chiral Selenoxide” Journal of Organic Chemistry, 2005, vol. 70, No. 13, pp. 5020-5027.

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