Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1997-05-06
1998-05-26
Ambrose, Michael G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C07C32341
Patent
active
057568235
ABSTRACT:
The present invention relates to glutathione monoester sulfonate represented by formula (I): ##STR1## (wherein R.sup.1 represent lower alkyl, and R.sup.2 represents lower alkyl, or substituted or unsubstituted aryl) which readily crystallizes and has high stability, and a simple process for producing the same. According to the process, the product having high purity can be obtained in high yields.
REFERENCES:
patent: 4709013 (1987-11-01), Nagano
patent: 5525628 (1996-06-01), Nicola et al.
"Transport of glutathione, as y-glutamylcysteinylglycyl ester, into liver and kidney," pp. 5258-5260. Sep. 1983 vol. 80 by R. Puri, et al.
Glutathione Monoethyl Ester: High-Performance Liquid Chromatographic Analysis and Direct Preparation of the Free Base Form by E. Campbell, et al pp. 21-25 (1989) vol. 183.
Chujo Iwao
Kasai Masaji
Kato Sachiko
Mimura Yukiteru
Ogasa Takehiro
Ambrose Michael G.
Kyowa Hakko Kogyo Co. Ltd.
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