Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Containing at least one abnormal peptide link – e.g. – gamma...
Patent
1986-05-30
1987-11-24
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Containing at least one abnormal peptide link, e.g., gamma...
530331, C07K 702, C07K 508
Patent
active
047090138
ABSTRACT:
Sulfates of glutathione monoalkyl esters (alkyl.gamma.-L-glutamyl-L-cysteinylglycinates) are new and can be prepared by reaction of glutathione with an alcohol in the presence of sulfuric acid. This process forms virtually no diesters, which are toxic compounds and must be completely removed when the sulfates are used as medicine. In addition, since pure glutathione monoester sulfates can be isolated from reaction mixture, high-purity free glutathione monoesters, which have importance as therapeutical and preventive medicines, can be obtained by treatment with a neutralizer or by mere desalting.
REFERENCES:
Chem. Abstr., vol. 62, (1965), 9567h.
Chem. Abstr., vol. 62, (1965), 869c&h.
Chem. Abstr., vol. 86, (1977), 52093c.
Chem. Abstr., vol. 76, (1972), 124283.
Chem. Abstr., vol. 84, (1976), 161001.
Chem. Abstr., vol. 10070c.
Chem. Abstr., vol. 58, (1963), 9471c.
Proc. Natl. Acad. Sci., 80, 5258-60 (1983).
Phillips Delbert R.
Yamanouchi Pharmaceutical Co. Ltd.
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