Glutaryl 7-ACA derivatives and processes for obtaining them

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540230, C07D50159, C07D50114, C07D50128, C07D50124, C07D50116

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active

060051019

ABSTRACT:
A compound having the following general formula (I): ##STR1## where R is a hydrogen atom; a linear or branched C.sub.1 -C.sub.4 alkyl group, unsubstituted or substituted by at least a phenyl group or at least a hydrogen atom; a benzyl group substituted by at least a linear or branched C.sub.1 -C.sub.4 alkyl or alkoxy group or a nitro group; a silyl substituted by at least a linear or branched, unsubstituted or substituted C.sub.1 -C.sub.4 alkyl group; n is 0 or 1; and Y is a radical of formula ##STR2## wherein A is H, OH, Cl, CH.sub.2, CH.sub.2 X, where X is F, Cl, Br, I, OH or OR' and R' is COCH.sub.3 or a linear or branched, unsubstituted or substituted C.sub.1 -C.sub.4 alkyl group and - - - represents a single or a double bond, with the proviso that when n=0 and R is H, R' is not a methyl group.

REFERENCES:
patent: 3912589 (1975-10-01), Smith
patent: 5660711 (1997-08-01), Walker
patent: 5773435 (1998-06-01), Kadow
Mazzeo, Chem. and Industry 1976, 325, Apr. 1976.
Vrudhula, Bioconjugate Chem 4, 334, 1993.

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