Glutarimide derivatives for treating oestrogen-dependent tumors

Details Glutarimide derivatives for treating oestrogen-dependent tumors Glutarimide derivatives for treating oestrogen-dependent tumors

1985-07-11

1987-05-26

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546193, A61K 31445, C07D40104

Patent

active

046686894

ABSTRACT:
In the treatment of oestrogen-dependent tumors, it is desirable to improve the therapy obtainable from the compound aminoglutethimide. It has now been found that 3-ethyl-3-(4-pyridyl)glutarimide derivatives of formula ##STR1## wherein: (a) R.sup.1 represents an ethyl group and R.sup.2 represents a methyl group, an alkyl or cycloalkyl group having 3 to 10 carbon atoms, or a fluoroalkyl group having 2 to 10 carbon atoms;

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