Glutaraldehyde and formalin detoxified bordetella toxin vaccine

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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4242361, 42419711, 530403, 530404, 530405, 530406, 530409, 530410, A61K 3910, A61K 39385, C07K 14235, C07K 1700

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active

055783082

ABSTRACT:
A detoxified B. pertussis toxin or antigenic preparation is described, which is characterized by stability to reversion to toxicity upon storage at 4.degree.-8.degree. C. and at temperatures above 23.degree. C. Also provided are methods for producing detoxified pertussis toxin and vaccines containing same.

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