Glutaminase, glutaminase gene, novel recombinant DNA, and...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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C435S110000, C435S320100, C435S252300

Reexamination Certificate

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06919195

ABSTRACT:
Glutaminase which comprises (a) a protein comprising an amino acid sequence shown in SEQ ID NO: 2, or (b) a protein which comprises an amino acid sequence having deletion, substitution, or addition of one or plurality of amino acids relative to the amino acid sequence (a), and has glutaminase activity. A glutaminase gene which encodes (a) a protein comprising an amino acid sequence shown in SEQ ID NO: 2, or (b) a protein which comprises an amino acid sequence having deletion, substitution, or addition of one or a plurality of amino acids relative to the amino acid sequence (a), and has glutaminase activity. The present invention enables glutaminase to be produced efficiently and thus greatly contributes to the relevant industries.

REFERENCES:
patent: 6312939 (2001-11-01), Roberts et al.
patent: 2002/0106782 (2002-08-01), Ito et al.
patent: 2004/0082053 (2004-04-01), Machida et al.
Yamamoto, S., et al. (1974) J. Ferment. Technol. 52(8), 570-576.
Yano, T., et al. (1988) J. Ferment. Technol. 66(2), 137-143.
K. Koibuchi, et al., Applied Microbiology and Biotechnology, vol. 54, No. 1, XP-002191327, pp. 59-68, “Molecular Cloning and Characterization of a Gene Encoding Glutaminase FromAspergillus oryzae”, Jul. 2000.

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