Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2009-03-24
2011-12-06
Raghu, Ganapathirama (Department: 1652)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C435S069100, C435S232000, C435S320100, C424S094100, C424S094500, C436S023000, C436S023000, C436S023000
Reexamination Certificate
active
08071563
ABSTRACT:
The invention relates to a novel Glutamic Acid Decarboxylase (GAD). More specifically, novel DNA and protein sequences relating to GAD. Additionally, the invention discloses a novel composition and related methods for treating neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, epilepsy, and the like, using viral and non-viral delivery systems that deliver therapeutic agents to specific regions of the brain. More specifically, using an adeno-associated viral vector to deliver a nucleotide sequence encoding a novel glutamic acid decarboxylase (GAD) to specific regions of the brain that are over stimulated or disinhibited in various diseases, including neurodegenerative diseases.
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Kapadia et al., &#
Bland Ross
Fitzsimons Helen
Neurologix, Inc.
Nutter & McClennen & Fish LLP
Raghu Ganapathirama
Xixis George A.
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