Glutamate receptors and utilization thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S069100, C435S252300, C435S320100

Reexamination Certificate

active

10922166

ABSTRACT:
An isolated DNA molecule which encodes a novel glutamate receptor and a transformed cell expressing the receptor are provided.

REFERENCES:
patent: 5385831 (1995-01-01), Mulvihill et al.
Masu et al. Sequence and Expression of a Metabotropic Glutamate Receptor. Feb. 28, 1991, Nature 349:760-765.
Berk, M. et al., “Platelet Glutamate Receptor Supersenitivity in Major Depressive Disorder”,Clinical Neuropharmacology, vol. 24, No. 3, pp. 129-132, (2001).
Karim, F. et al., “Metabotropic Glutamate Receptor Subtypes 1 and 5 Are Activators of Extracellular Signal-Regulated Kinase Signaling Required for Inflammatory Pain in Mice”,The Journal of Neuroscience, vol. 21, No. 11, pp. 3771-3779, (2001).
Berk, M. et al., “The Specificity of Platelet Glutamate Receptor Supersensitivity in Psychotic Disorders”,Life Sciences, vol. 66, No. 25, pp. 2427-2432, (2000).
Carlton, S. M. et al., “Inflammation-induced changes in peripheral glutamate receptor populations”,Brian Research, vol. 820, pp. 63-70, (1999).
Haxhiu, M. A. et al., “The role of excitatory amino acids in airway reflec responses in anesthetized dogs”,Journal of the Autonomic Nervous System, vol. 67, pp. 192-199, (1997).
Inagaki, N. et al.,. “Expression and role of ionotropic glutamate receptors in pancreatic islet cells”,The FASEB Journal, vol. 9, pp. 686-691, (1995).
Erdö, S. L., “Exitatory amino acid receptors in the mammalian periphery”,TRENDS in Pharmacological Sciences, vol. 12, pp. 426-429, (1991).
Aas, P. et al., “Stimulation of peripheral cholinergic nerves by glutamate indicates a new peripheral glutamate receptor”,European Journal of Pharmacology, vol. 164, pp. 93-102, (1989).
Said, S. I. et al., “Glutamate signalling in the lung”,TRENDS in Pharmacological Sciences, vol. 22, No. 7, pp. 344-345, (2001).
Skerry, T. M. et al., “Glutamate signalling in non-neuronal tissues”,TRENDS in Pharmacological Sciences, vol. 22, No. 4, pp. 174-181, (2001).
Bray, G. A., “Afferent signals regulating food intake”,Proceeding of the Nutrition Society, vol. 59, pp. 373-384, (2000).
Bray, G. A., “Nutrient Balance and Obesity: An Approach to Control of Food Intake in Humans”,Medical Clinics of North America, vol. 73, No. 1, pp. 29-45, (1989).
Mei, N., “Recent studies on intestinal vagal afferent innervation. Functional implications”,Journal of the Autonomic Nervous System, vol. 9, pp. 199-206, (1983).
Mei, N. et al., “Current data and ideas on digestive sensitivity”,Journal of the Autonomic Nervous System, vol. 41, pp. 15-18, (1992).
Mei, N., “Intestinal Chemosensitivity”,The American Physiological Society, vol. 65, No. 2, pp. 211-237, (1985).
Pin, J. et al., “Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes”, Proc. Natl. Acad. Sci. USA, vol. 89, pp. 10331-10335, (1992).
Kasahara, J. et al., “Insitol phosopholipid metabolism in Xenopus oocytes mediated by endogenous Goand Giproteins”,Federation of European Biochemical Societies, vol. 355, pp. 41-44, (1994).
Takahashi, K. et al., “Role of the Large Extracellular Domain of Metabotropic Glutamate Receptors in Agonist Selectivity Determination”,The Jounral of Biological Chemistry, vol. 268, No. 26, pp. 19341-19345, (1993).
Naples, M. A. et al., “Pharamcological profiles of the metabotropic glutamate receptor ligands [3H] L-AP4 and [3H] CPPG”,Neuropharmacology, vol. 40, pp. 170-177, (2001).
Thomsen, C. et al., “Cloning and Characterization of a Metabotropic Glutamate Receptor, mGluR4b”,Neuropharmacology, vol. 36, No. 1, pp. 21-30, (1997).
Adams, S. R. et al., “Fluorescence ratio imaging of cyclic AMP in single cells”,Nature, vol. 349, pp. 694-697, (1991).
McConnell, H. M. et al., “The Cytosensor Microphysiometer: Biological Applications of Silicon Technology”,Science, vol. 257, pp. 1906-1912, (1992).
Hermans, E. et al., “Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors”, Biochem. J., vol. 359, pp. 465-484, (2001).
Niijima, A., “Effects of Oral and Intestinal Stimulation with Umami Substance on Gastric Vagus Activity”,Physiology&Behavior, vol. 49, pp. 1025-1028, (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Glutamate receptors and utilization thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Glutamate receptors and utilization thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glutamate receptors and utilization thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3803084

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.