Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1995-06-06
1998-04-14
Chan, Christina Y.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303891, 5303879, C07K 1628
Patent
active
057392919
ABSTRACT:
The present invention discloses novel DNAs that encode proteins having electrophysiological and pharmacological properties characteristic of glutamate receptors. The glutamate receptors are exemplified by proteins encoded by representative cDNA clones GluR1, GluR2, GluR3, GluR4, GluR5, GluR6 and GluR7, fragments thereof, and functional combinations of these glutamate receptor proteins and/or fragments. DNA sequences from the cDNA clones for GluR1, GluR2, GluR3, GluR5 and GluR5 are especially useful as probes, thus enabling those skilled in the art to identify, without undue experimentation, other members of the L-glutamate receptor family.
REFERENCES:
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Harris et al., TiBTech, 1993, 11:43.
Hampson et al., J Biol Chem., 264:13329, 1989.
Hampson et al., J Biol Chem, 263:2500, 1988.
Bettler Bernhard
Boulter James R.
Heinemann Stephen F.
Hollmann Michael
Jensen Jan Egebejerg
Cech Emma
Chan Christina Y.
Reiter Stephen E.
The Salk Institute for Biological Studies
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