Glucuronide repressors and uses thereof

Details Glucuronide repressors and uses thereof Glucuronide repressors and uses thereof

1997-06-25

1999-03-09

Ketter, James

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 9141, 435243, 4353201, 435325, 435410, 536 234, 536 235, 536 241, C12P 2100, C12N 1570, C12N 500, C07H 2104

Patent

active

058799060

ABSTRACT:
Clones containing a sequence encoding a glucuronide repressor are described. The nucleotide and amino acid sequences of a repressor (gusR) are presented. A glucuronide repressor is used to control expression of a transgene, detect glucuronides in a sample, and isolate glucuronides from a sample, among other uses.

REFERENCES:
patent: 5268463 (1993-12-01), Jefferson
Blanco et al., "Cloning and Endonuclease Restriction Analysis of uidA and uidR Genes in Escherichia coli K-12: Determination of Transcription Direction for the uidA Gene," Journal of Bacteriology 149(2):587-594, 1982.
Blanco, "Transcriptional and translational signals of the uidA gene in Escherichia coli K12," Mol Gen Genet 208:490-498, 1987.
Ritzenthaler et al., "Interchangeability of Repressors for the Control of the uxu and uid Operons in E. coli K12," Mol Gen Genet 191:263-270, 1983.
Wilson and Jefferson, "The GusR repressor of Escherichia Coli," EMBL Database Entry Ecuidaa; Accession No. M 14641(Version 8), 1995.

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