Glucosyltransferase inhibitors, as well as dental caries prevent

Details Glucosyltransferase inhibitors, as well as dental caries prevent Glucosyltransferase inhibitors, as well as dental caries prevent

1994-01-24

1995-04-25

Richter, Johann

Drug, bio-affecting and body treating compositions

Dentifrices

424 58, A61K 716, A61K 726

Patent

active

054096928

ABSTRACT:
Glucosyltransferase inhibitors containing as an active ingredient an extract of fermented tea leaves are described. Illustrative examples of the fermented tea leaves include Oolong tea, black tea and Pu-erh tea. Also described are foods or beverages for the prevention of dental caries, which contain an effective amount of one of such inhibitors. Dental caries can be prevented by taking such foods or beverages.

REFERENCES:
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Hattori, et al., "Effect of Tea Polyphenols on Glucan Synthesis by Glucosyltransferase from Streptococcus Mutans, Chem. Pharm. Bull", 38 (3) 1990, 717-720.
Dorland's Illustrated Medical Dictionary, 24th edition, Sanders, Philadelphia, 1965.
Chemical Abstracts vol. 104, No. 15, 14 Apr. 1986, p. 595, abstract no. 128611h, Columbus, Ohio, US; S. Kashket et al.: "In-vitro inhibition of glucosyltransferase from the dental plaque bacterium Streptococcus mutans by common beverages and food extracts." Arch. Oral Biol. 1985, vol. 30, Nos. 11, 12 pp. 821-826 *abstract*.
Patent Abstracts of Japan vol. 14, No. 176 (C-707) (4119), 9 Apr. 1990; & JP-A-225413 (Itouen K.K.) 26 Jan. 1990 *the whole document*.
Chemical Abstracts vol. 99, 15 Aug. 1983, p. 432, abstract no. 52157v, Columbus, Ohio, US; R. L. Spiers: "Correlations between the concentration of fluoride and some other constituents in tea infusions and their possible dental caries-preventive effect." & Arch. Oral. Biol. 1983, vol. 28, No. 6, pp. 471-475 *abstract*.
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Patent Abstracts of Japan vol. 13, No. 431 (C-640) (3779), 26 Sep. 1989; & JP-A-1168235 (Meiji Seika Kaisha Ltd.) 3 Jul. 1989 *the whole document*.
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