Glucose sensor with gel-immobilized glucose oxidase and gluconol

Details Glucose sensor with gel-immobilized glucose oxidase and gluconol Glucose sensor with gel-immobilized glucose oxidase and gluconol

1988-11-28

1992-01-21

Lacey, David L.

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

435 14, 435177, 435817, C12M 140, C12Q 154

Patent

active

050827863

ABSTRACT:
A glucose sensor in which a gel is in contact with a pH sensing element. The gel contains immobilized glucose oxidase and gluconolactonase (EC 3.1.1.17). Gluconolactonase is present in an amount effective to accelerate the hydrolysis of D-glucono-.delta.-lactone.

REFERENCES:
patent: 4066512 (1978-01-01), Lai et al.
patent: 4224125 (1980-09-01), Nakamura et al.
patent: 4601981 (1986-07-01), Vieth et al.
Pocker et al, "Hydrolysis of D-Glucono-.delta.-lactone", Journal of the American Chemical Society, vol. 95, No. 1, Jan. 10, 1973, pp. 113-119.
Henozato et al, "Multi-Enzyme Electrode Using Hydrogen-Ion-Sensitive Field-Effect Transistors", IEEE Transactions on Electron Devices, vol. ED33, No. 1, Jan. 1988, pp. 47-51.
Hanazote et al, "Glucose Sensitive Field-Effect Transistor with a Membrane Containing Co-Immobilized Gluconolactonase and Glucose Oxidase", 9-15-88, pp. 47-59.
The 1984 Enzyme Nomenclature Book, 1984, pp. 50, 51 and 73-74.
Dixon and Webb, Enzymes, 2nd Ed., Academic Press Inc., 1964, pp. 16, 17, 734.
"Glucoamylase and Glucose Oxidase Preparations and Their Combined Application for Conversion of Mattose to Gluconic Acid", Biotechnology and Bioengineering, vol. 19 (1977), pp. 185-198.
"Purification and Partial Characterization of Beef Liver Gluconolactonase", Archives of Biochemistry and Biophysics, vol. 192, No. 2, Feb. 1979, pp. 482-488.
"pH-Based Enzyme Potentiometric Sensors", Anal. Chem., vol. 57, pp. 1920-1923.
"pH-Based Enzyme Potentiometric Sensors", Anal. Chem., vol. 57, pp. 1924-1925.
"Immobilized Enzyme Electrode Probes", Solid Phase Biochemistry, published by John Wiley & Sons, New York (1983), pp. 479-505.

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