Glucose sensitive FET sensor and method of making same

Chemistry: electrical and wave energy – Apparatus – Electrolytic

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204418, 427 58, 4273855, 4274301, 4274432, 435 14, 435817, 436531, 436806, G01N 27327

Patent

active

055430244

ABSTRACT:
A glucose sensitive FET sensor is provided which includes a substrate, a source electrode formed in the substrate, a drain electrode formed in the substrate, a hydrogen ion sensitive film formed on the substrate to cover the source electrode and the drain electrode, and a thin enzyme immobilized membrane formed on the hydrogen ion sensitive film and containing glucose oxidase and gluconolactonase. Also provided is a method of producing a glucose sensitive FET sensor which includes the steps of preparing an enzyme immobilized membrane as a thin film containing glucose oxidase and gluconolactonase and forming the membrane on a hydrogen ion sensitive film which is formed on a substrate to cover a source electrode and a drain electrode, both of which are formed in the substrate.

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Hanazato et al, "Proceedings of the International Meeting on Chemical Sensors", pp. 513-518, 1983 Month unavailable.
Pocker et al, "Hydrolysis of D-Glucono-8-lactone. I. General Acid-Base Catalysis, Solvent Deuterium Isotope Effects, and Transition State Characterization", J. Amer. Chem. Soc. 95, pp. 113-119 (1973) Month unavailable.

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