Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-o
Reexamination Certificate
2011-08-23
2011-08-23
Gakh, Yelena G (Department: 1777)
Chemistry: analytical and immunological testing
Heterocyclic carbon compound
Hetero-o
C436S094000, C422S068100, C422S073000
Reexamination Certificate
active
08003397
ABSTRACT:
A polymeric sensing fluid for detecting the presence of glucose and systems and methods of its use are generally disclosed. The polymeric sensing fluid includes a polymer in a solvent (e.g., an aqueous solvent). The polymer has a plurality of boronic acid moieties extending from its polymeric backbone. As such, the polymeric sensing fluid is configured to increase in viscosity upon addition of glucose due to crosslinking between the boronic acid moieties of the polymer and glucose.
REFERENCES:
patent: 2006/0089265 (2006-04-01), Hanes et al.
Li et al. (Li S.; Anderson, J.; Wang, Q. “Synthesis and Preparation of a Novel Glucose Sensing Fluid,” ACS Southeastern Regional Meeting (SERMACS), Greenville, SC, Oct. 24-27, 2007, see entry No. 34 on p. 4).
Kitano et al. (“Glucose-responsive complex formation between poly(vinyl alcohol) and poly(N-vinyl-2-pyrrolidone) with pendent phenylboronic acid moieties,” Makromol. Chem., Rapid Commun. 1991, 12, 227-233).
Shiomori et al. (“Thermoresponsive Properties of Sugar Sensitive Copolymer of N-Isopropylacrylamide and 3-(Acrylamido)phenylboronic Acid,” Macromol. Chem. Phys. 2004, 205, 27-34.).
Gabai et al. (“Characterization of the Swelling of Acrylamidophenylboronic Acid-Acrylamide Hydrogels upon Interaction with Glucose by Faradaic Impedance Spectroscopy, Chronopotentiometry, Quartz-Crystal Microbalance (QCM), and Surface Plasmon Resonance (SPR) Experiments,” J. Phys. Chem. B 2001, 105, 8196-8202).
Kuzimenkova et al. (“Boronate-Containing Copolymers: Polyelectrolyte Properties and Sugar-Specific Interaction with Agarose Gel,” Macromol. Biosci. 2006, 6, 170-178.).
Kitano et al. (“A novel drug delivery system utilizing a glucose responsive polymer complex between poly(vinyl alcohol) and poly(N-vinyl-2-pyrrolidone) with a phenylboronic acid moiety,” Journal of Controlled Release 1992, 19, 162-170).
Alexeev et al. “High Ionic Strength Glucose-Sensing Photonic Crystal,” Anal. Chem. 2003, 75, 2316-2323.
Arnold et al., A membrane-moderated, conductimetric sensor for the detection and measurement of specific organic solutes in aqueous solutions,Journal of Membrane Science167, 2000, pp. 227-239.
Asher et al., Photonic Crystal Carbohydrate Sensors: Low Ionic Strength Sugar Sensing,J. Am. Chem., vol. 125, No. 11, 2003, pp. 3322-3329.
Diem et al., Clinical Performance of a Continuous Viscometric Affinity Sensor for Glucose,Diabetes Technology&Therapeutics, vol. 6, No. 6, 2004, pp. 790-799.
Enker et al., Augmentation of Tumor-Specific Immunogenicity by Concanavalin A in the Morris Hepatoma 5123,Journal of Surgical Research, vol. 16, No. 1, Jan. 1974, pp. 66-68.
Fang et al., Progress in Boronic Acid-Based Fluorescent Glucose Sensors,Journal of Fluorescence, vol. 14, No. 5, Sep. 2004, pp. 481-489.
Hawkins et al., The Reaction ofo-(Bromomethyl)benzeneboronic Anhydride with Primary Amines,J. Org. Chem., vol. 32(3), Mar. 1967, pp. 597-600.
Hegedus et al., Palladium-Assisted Cyclization-lnsertion Reactions. Synthesis of Functionalized Heterocycles,Journal of the American Chemical Society, 102:10, May 7, 1980, pp. 3583-3587.
Ivanov, et al., “Synthesis of boronate-containing copolymers of N, N-dimethylacrylamide, their interaction with poly(vinyl alcohol) and rheological behaviour of the gels”, Polymer, vol. 45 (2004), pp. 2495-2505.
Kataoka et al., Immunogenicity and Amplifier Cell Production by Tumor Vaccines Enhanced by Concanavalin A,Gann, 73, Apr. 1982, pp. 193-205.
Kitano et al., Interfacial Recognition of Sugars by Novel Boronic Acid-Carrying Amphiphiles Prepared with a Lipophilic Radical Initiator,Langmuir, vol. 14, No. 1, 1998, pp. 165-170.
Kuivila et al., Areneboronates from Diols and Polyols,J. Org. Chem., 19 (5), 1954, pp. 780-783.
Kuzimenkova et al., Boronate-Containing Copolymers: Polyelectrolyte Properties and Sugar-Specific Interaction with Agarose Gel,Macromol. Biosci., 6, 2006, pp. 170-178.
Lei et al., A Hydrogel-Based Implantable Mirocmachined Transponder for Wireless Glucose Measurement,Diabetes Technology&Therapeutics, vol. 8, No. 1, 2006, pp. 112-122.
Lorand et al., Polyol Complexes and Structure of the Benzeneboronate Ion,J. Org. Chem., 24 (6), Jun. 1959, pp. 769-774.
Erna Möller, Contact-Induced Cytotoxicity by Lymphoid Cells Containing Foreign Isoantigens,Science, New Series, vol. 147, No. 3660, Feb. 19, 1965, pp. 873-874 and 879.
Yan et al., Boronolectins and Fluorescent Boronolectins: An Examination of the Detailed Chemistry Issues Important for the Design,Medicinal Research Reviews, vol. 25, No. 5, 2005, pp. 490-520.
Yang et al., Boronic Acid Compounds as Potential Pharmaceutical Agents,Medicinal Research Reviews, vol. 23, No. 3, 2003, pp. 346-368.
Zhao et al., A MEMS viscometric sensor for continuous glucose monitoring,Journal of Micromechanics and Microengineering, 17, 2007, pp. 2528-2537.
Phillips et al., Abstract of Lectin-dependent and anti-CD3 induced cytotoxicity are preferentially mediated by peripheral blood cytotoxic T lymphocytes expressing Leu-7 antigen,The Journal of Immunology, vol. 136, Issue 5, 1986, pp. 1579-1585.
CDC Diabetes, National Diabetes Fact Sheet, United States, 2005, General Information, 10 pages.
Information Sheet from Medtronic—Introducing the Guardian® REAL-Time Continuous Glucose Monitoring System, 2009, 3 pages.
Information Sheet from Medtronic—MiniMed Paradigm® REAL-Time Insulin Pump and Continuous Glucose Monitoring System, 2009, 2 pages.
Li Siqi
Wang Qian
Adams Michelle M
Dority & Manning P.A.
Gakh Yelena G
University of South Carolina
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