Glucose-6-phosphate dehydrogenase conjugates useful in polyiodot

Details Glucose-6-phosphate dehydrogenase conjugates useful in polyiodot Glucose-6-phosphate dehydrogenase conjugates useful in polyiodot

1987-11-24

1989-07-11

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 14, 435 26, 435188, 436500, G01N 33536, G01N 33542

Patent

active

048471950

ABSTRACT:
Polyiodothyronine analog conjugates to glucose-6-phosphate dehydrogenase (G6PDH) are provided which find use in the determination of polyiodothyronine compounds, particularly thyroxine, normally in physiological fluids, such as serum. The G6PDH enzyme activity can be substantially reduced when bound to antibodies specific to polyiodothyronine as compared to the free or unbound polyiodothyronine analog enzyme conjugates. The polyiodothyronine analog is conjugated to the G6PDH by a linking group having a chain one atom in length.

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United States Patent Office: Classification Definitions, Class 260, 1971.
United States Patent Office: Classification Definitions, Class 260, p. 260-4A, Oct. 1971.

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