Glucose-6-phosphate dehydrogenase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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Details

C435S252300, C435S320100, C435S069100, C435S071100, C435S440000, C435S106000, C435S113000, C435S115000, C536S023200, C536S023700

Reexamination Certificate

active

07078204

ABSTRACT:
The present invention relates to a novel glucose-6-phosphate dehydrogenase (hereinafter referred to as “G6PD”) derived from a bacterium belonging to the genusCorynebacterium, a DNA encoding the enzyme, a recombinant DNA comprising the DNA, a transformant comprising the recombinant DNA, a transformant comprising the DNA on its chromosome, and a process for producing L-amino acid or G6PD which comprises culturing the transformant.According to the present invention, a modified G6PD and a DNA encoding the G6PD are obtained, and the productivity of L-amino acid by a microorganism can be improved by using the modified G6PD.

REFERENCES:
patent: 2003/0175911 (2003-09-01), Hans et al.
patent: 09-224661 (1997-09-01), None
patent: 9-224662 (1997-09-01), None
patent: 01/04322 (2001-01-01), None
Sahm, et al., “Pathway Analysis and Metabolic Engineering inCorynebacterium glutamicum”, Med. Fac. Landbouww., vol. 65, No. 3A (2000), pp. 221-229.
Sahm, et al., “Pathway Analysis and Metabolic Engineering inCorynebacterium glutamicum”, Biol. Chem., vol. 381, No. 9/10 (2000), pp. 899-910.

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