Glucosamine derivative and liposome containing the same as membr

Details Glucosamine derivative and liposome containing the same as membr Glucosamine derivative and liposome containing the same as membr

1992-06-08

1994-04-19

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

536 41, 536 187, B01F 1756, A61K 9127, B01J 1302, C07H 1306, C07H 15104

Patent

active

053043804

ABSTRACT:
Disclosed are a glucosamine derivative represented by the following formula [I] or a pharmacologically acceptable salt thereof, and a liposome containing the glucosamine derivative as a membrane constituting component: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and m represent the following R.sup.1 and R.sup.2 ;

REFERENCES:
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patent: 4485054 (1984-11-01), Mezei et al.
patent: 4818816 (1989-04-01), Petitou et al.
patent: 4883665 (1989-11-01), Miyazima et al.
patent: 5032505 (1991-07-01), Pierce et al.
patent: 5041427 (1991-08-01), Takayama et al.
patent: 5059685 (1991-10-01), Conti
"Eur. J. Biochem. 47" (1974) pp. 173-179.
"Journal of the Neurological Sciences" 1977, 31: pp. 173-179.
"Chemistry Letters" Cmltag (11), 1980 pp. 1373-1376.
"Drug Delivery System" vol. 2, No. 1, 1987, pp. 48-51.
Katsura et al., 111 Chemical Abstracts No. 45278y (1988).
Ekimoto et al., 112 Chemical Abstracts No. 165001v (1989).
Anderson, et al., Bacterial Lipopolysaccharides, 1983, pp. 255-275.
Chemical Abstracts, vol. 100, No. 13, Mar. 26, 1984, p. 693, 103782u, Chem. Abstr. Eleventh Collective Index, vols. 96-105, 1982-1986, Formula C38H73NO7; Formula C73H117N08.
Chemical Abstracts, vol. 107, No. 5, Aug. 3, 1987, p. 402, 46060a, and Chemical Formula Index, vol. 107, 1987, Formula C24H47NO6.

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