Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2001-03-15
2008-12-16
Jiang, Shaojia Anna (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S023000, C514S025000
Reexamination Certificate
active
07465712
ABSTRACT:
The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula:wherein R1represents a hydrogen atom or a hydroxy(lower alkyl) group; and R2represents a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a hydroxy(lower alkyl) group, a hydroxy(lower alkoxy) group, a hydroxy(lower alkylthio) group etc., and salts thereof, which have an excellent inhibitory activity in human SGLT2 and are useful as agents for the prevention or treatment of diabetes, obesity etc., and intermediates thereof.
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Akira Oku, et al.; Antidiabetic effect of T-1095, an inhibitor of Na+-glucose cotransporter, in neonatally streptozotocin-treated rats; European Journal of Pharmacology 39 (2000) pp. 183-192.
Fujikura Hideki
Fushimi Nobuhiko
Nishimura Toshihiro
Tatani Kazuya
Jiang Shaojia Anna
Kissei Pharmaceutical Co. Ltd.
McIntosh, III Traviss C
Sughrue & Mion, PLLC
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