Glucopyranosyl-substituted benzonitrile derivatives,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C536S001110, C536S018700

Reexamination Certificate

active

07745414

ABSTRACT:
Glucopyranosyl-substituted benzonitrile derivatives as defined herein, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The compounds according to the invention are suitable for the treatment of metabolic disorders.

REFERENCES:
patent: 4602023 (1986-07-01), Kiely et al.
patent: 4786023 (1988-11-01), Kiely et al.
patent: 4786755 (1988-11-01), Kiely et al.
patent: 6414126 (2002-07-01), Ellesworth et al.
patent: 6515117 (2003-02-01), Ellesworth et al.
patent: 6627611 (2003-09-01), Tomiyama et al.
patent: 6774112 (2004-08-01), Gougoutas
patent: 6936590 (2005-08-01), Washburn et al.
patent: 7169761 (2007-01-01), Tomiyama et al.
patent: 7202350 (2007-04-01), Imamura et al.
patent: 7371732 (2008-05-01), Eickelmann et al.
patent: 7375090 (2008-05-01), Himmelsbach et al.
patent: 7393836 (2008-07-01), Eckhardt et al.
patent: 7417032 (2008-08-01), Eckhardt et al.
patent: 7419959 (2008-09-01), Eckhardt et al.
patent: 7579449 (2009-08-01), Eckhardt et al.
patent: 2002/0137903 (2002-09-01), Ellsworth et al.
patent: 2003/0064935 (2003-04-01), Gougoutas
patent: 2003/0114390 (2003-06-01), Washburn et al.
patent: 2004/0138148 (2004-07-01), Fushimi et al.
patent: 2004/0138439 (2004-07-01), Deshpande et al.
patent: 2005/0065098 (2005-03-01), Fujikura et al.
patent: 2005/0124555 (2005-06-01), Tomiyama et al.
patent: 2005/0209166 (2005-09-01), Eckhardt et al.
patent: 2006/0009400 (2006-01-01), Eckhardt et al.
patent: 2006/0019948 (2006-01-01), Eckhardt et al.
patent: 2006/0025349 (2006-02-01), Eckhardt et al.
patent: 2006/0035841 (2006-02-01), Eckhardt et al.
patent: 2006/0063722 (2006-03-01), Washburn et al.
patent: 2006/0074031 (2006-04-01), Eckhardt et al.
patent: 2006/0142210 (2006-06-01), Eckhardt et al.
patent: 2006/0189548 (2006-08-01), Himmelsbach et al.
patent: 2006/0234953 (2006-10-01), Himmelsbach et al.
patent: 2006/0251728 (2006-11-01), Himmelsbach et al.
patent: 2006/0258749 (2006-11-01), Eckhardt et al.
patent: 2007/0004648 (2007-01-01), Himmelsbach et al.
patent: 2007/0027092 (2007-02-01), Himmelsbach et al.
patent: 2007/0049537 (2007-03-01), Eckhardt et al.
patent: 2007/0054867 (2007-03-01), Eckhardt et al.
patent: 2007/0073046 (2007-03-01), Eckhardt et al.
patent: 2007/0249544 (2007-10-01), Himmelsbach et al.
patent: 2007/0259821 (2007-11-01), Eckhardt et al.
patent: 2009/0023913 (2009-01-01), Eckhardt et al.
patent: 2 388 818 (2001-04-01), None
patent: 2 494 177 (2004-02-01), None
patent: 2 508 024 (2004-06-01), None
patent: 2 508 226 (2004-06-01), None
patent: 2 557 269 (2005-09-01), None
patent: 2 557 320 (2005-09-01), None
patent: 2 557 801 (2005-10-01), None
patent: 2 573 777 (2006-02-01), None
patent: 0 206 567 (1986-06-01), None
patent: 1344780 (2003-09-01), None
patent: 1 385 856 (2004-02-01), None
patent: 1224195 (2005-05-01), None
patent: 1 553 094 (2005-07-01), None
patent: 1 609 785 (2005-12-01), None
patent: 58/164502 (1983-09-01), None
patent: 62/030750 (1987-02-01), None
patent: 11/124392 (1999-05-01), None
patent: 2001/288178 (2001-10-01), None
patent: 2003/511458 (2003-03-01), None
patent: 2004/359630 (2004-12-01), None
patent: 98/31697 (1998-07-01), None
patent: 01/27128 (2001-04-01), None
patent: 01/74834 (2001-10-01), None
patent: 02/064606 (2002-08-01), None
patent: 02/083066 (2002-10-01), None
patent: 03/099836 (2003-12-01), None
patent: 2004/013118 (2004-02-01), None
patent: 2004/052902 (2004-06-01), None
patent: 2004/052903 (2004-06-01), None
patent: 2004/063209 (2004-07-01), None
patent: 2004/076470 (2004-09-01), None
patent: 2004/080990 (2004-09-01), None
patent: 2005/012326 (2005-01-01), None
patent: 2005/012318 (2005-02-01), None
patent: 2005/085237 (2005-09-01), None
patent: 2005/085265 (2005-09-01), None
patent: 2005/092877 (2005-10-01), None
patent: 2006/011469 (2006-02-01), None
patent: 2006/034489 (2006-03-01), None
patent: 2006/064033 (2006-06-01), None
patent: 2006/089872 (2006-08-01), None
patent: 2006/108842 (2006-10-01), None
patent: 2006/117360 (2006-11-01), None
patent: 2006/120208 (2006-11-01), None
patent: 2007/014894 (2007-02-01), None
patent: 2007/025943 (2007-03-01), None
patent: 2007/028814 (2007-03-01), None
patent: 2007/031548 (2007-03-01), None
Adachi et al., “T-1095, a Renal Na+-Glucose Transport Inhibitor”, Metabolism, vol. 49 (8), 2000, 990-995.
Rachida Benhaddou et al; Tetra-n-Propylammonium Tetra-Oxoruthenate(VII): A Reagent of Choice for the Oxidation of Diversely Protected Glycopyranoses and Glycofuranoses to Lactones; Carbohydrate Research (1994) vol. 260 pp. 243-250.
Wolfgang Dohle et al; Copper-Mediated Cross-Coupling of Functionalized Arylmagnesium Reagents with Functionalized Alkyl and Benzylic Halides; Organic Letters (2001) vol. 3 No. 18 pp. 2871-2873.
Alois Fuerstner et al; Practical Method for the Rhodium-Catalyzed Addition of Aryl- and Alkenylboronic Acids to Aldehydes; Advanced Synthesis and Catalysis (2001) vol. 343 No. 4 pp. 343-350.
Asanori Hatsuda et al; A Practical Synthesis of Highly Functionalized Aryl Nitriles Through Cyanation of Aryl Bromides Employing Heterogeneous Pd/C; Tetrahedron Letters (2005) vol. 46 pp. 1849-1853; Elsevier Ltd.
Craig A Hutton et al; A Convenient Preparation of dityrosine Via Miyaura Borylation-Suzuki Coupling of Iodotyrosine Derivatives; Tetrahedron Letters (2003) vol. 44 pp. 4895-4898; Pergamon Press.
Takehiko Iida et al; Tributylmagnesium Ate Complex-Mediated Novel Bromine-Magnesium Exchange Reaction for Selective Monosubstitution of Dibromoarenes; Tetrahedron Letters (2001) vol. 42 pp. 4841-4844; Pergamon Press.
G. Erik Jagdmann, Jr; Synthesis of 5-(4-Substituted Benzyl)-2,4-Diaminoquinazolines as Inhibitors of Candida Albicans Dihydrofolate Reductase; Journal Heterocyclic Chemical (1995) vol. 32 pp. 1461-1465.
Ja Seo Koo et al; 2-Pyridyl Cyanate: A Useful Reagent for he Preparation of Nitriles; Synthetic Communications (1996) vol. 26 No. 20 pp. 3709-3713; Marcel Dekker, Inc.
Takeshi Kuribayashi, et al; c-Glycosylated Aryl tins: Versatile Building Blocks for Aryl C-Glycoside Glycomimetics; J. Carbohydrate Chemistry (1999) vol. 18, No. 4 pp. 371-382.
Takeshi Kuribayashi, et al; C-Glycosylated Diphenylmethanes and Benzophenones: The Stille Coupling Reaction of C-Glycosylated Aryl tins with Benzyl Bromides and Acid Chlorides; J. Carbohydrate Chemistry (1999) vol. 18, No. 4 pp. 393-401.
Takeshi Kuribayashi et al; Bis C-Glycosylated Diphenylmethanes for Stable Glycoepitope Mimetics; Syntletters (1999) vol. 6 pp. 737-740.
Sandrine Langle et al; Selective Double Suzuki Cross-Coupling Reactions. Synthesis of Unsymmetrical Diaryl (or Heteroaryl) Methanes; Tetrahedron Letters (2003) vol. 44 pp. 9255-9258; Pergamon Press.
Mark Mclaughlin et al; Suzuki-Miyaura Cross-Coupling of Benzylic Phospahates with Arylboronic Acids; Organic Letters (2005) vol. 7 No. 22 pp. 4875-4878.
Ouri Neamati, et al, “Depsides and Depsidones as Inhibiton of HIV-1 Integrase: Dimvery of Novel Inhibitors Through 3D Database Searclung”, J. Med. Chem., 1997, vol. 40, pp. 942-951.
Sabrina M. Nobre et al; Synthesis of Diarylmethane Derivatives from Pd-Catalyzed Cross-Coupling Reactions of Benzylic Halides with Arylboronic Acids; Tetrahedron Letters (2004) vol. 45 8225-8228.
Akira Oku, et al; T-1095, An Inhibitor or renal Na+-Glucose Cotransporters, May Provide a Novel Approach to Treating Diabetes; Diabetes (1999) vol. 48 pp. 1794-1800.
Richard J. Perner et al; 5,6,7-Trisubstituted 4-Aminopyrido[2,3-d]pyrimidines as Novel inhibitors of Adenosime Kinase; Journal of Medicinal Chemistry (2003) vol. 46 pp. 5249-5257.
Michael Bech Sommer et al; displacement of Halogen of 2-Halogeno-Substituted Benzonitriles with Carbonions. Preparation of (2-Cyanoaryl)arylacetonitriles; Journal of Organic Chemistry (1990) vol. 55 pp. 4817-4821.
Lasslo Revesz et al; SAR of Benzoylpylpyridines and Benzophenones as p38 Alpha MAP Kinase Inhibitors with Oral Activity; Bioorganic & Medicinal Chemistry Letters (2004) vol. 14 pp. 3601-3605.
Federica Stazi et al; Statistical Experimental Design-Driven Discovery of room-Temperature Conditions for Palladium-Catalyzed Cyanat

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Glucopyranosyl-substituted benzonitrile derivatives,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Glucopyranosyl-substituted benzonitrile derivatives,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glucopyranosyl-substituted benzonitrile derivatives,... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4160177

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.