Glucopyranose derivatives

Details Glucopyranose derivatives Glucopyranose derivatives

1989-04-14

1990-05-15

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536118, 536122, 536 54, 536 172, 536 175, 514885, A61K 3100, C07H 1300, C07H 1100, C07D30900

Patent

active

049259296

ABSTRACT:
This invention relates to glucopyranose compounds of formula (I) and (IA) ##STR1## and the non-toxic salts thereof wherein the substituents are as defined herein. Such materials possess enhancing activity of cellular immunity (e.g. mitogenic activity) to living tissue and therefore are useful as anti-tumor agents.

REFERENCES:
patent: 4304903 (1981-12-01), Nair et al.
patent: 4374831 (1983-02-01), Joseph et al.
patent: 4399126 (1983-08-01), Schaub et al.
patent: 4536572 (1985-08-01), Kim et al.
Agricultural and Biological Chemistry, vol. 48, No. 1, Jan. 1984, pp. 251-252, "Synthesis of Biologically Active, Novel Monosaccharide Analogs of Lipid A".
Chemical & Pharmaceutical Bulletin, vol. 33, No. 10, Oct. 1985, pp. 4621-4624, "Antitumor Activity and Biological Effects of Chemically Synthesized etc."

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