Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Lyase
Reexamination Certificate
2006-10-24
2006-10-24
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Lyase
C435S136000, C435S137000, C435S069100
Reexamination Certificate
active
07125704
ABSTRACT:
A novel gluconate dehydratase derived fromAchromobacter xylosoxidansand a gene encoding the gluconate dehydratase are provided. By reacting the gluconate dehydratase or a transformed cell containing the gene with an aldonic acid, the corresponding 2-keto-3-deoxyaldonic acid can be efficiently produced.
REFERENCES:
patent: 6562958 (2003-05-01), Breton et al.
Kersters et al (and properties of D-gluconate dehydratase from Achromobacter. Antonie Van Leewenhoek 37 (1971) 233-246.
R. Bender et al., “Enzymatic Synthesis of 2-Keto-3-deoxy-D-gluconate from D-Gluconate,”Analytical Biochemistry, 1974, pp. 275-279, vol. 61, Academic Press, Inc.
K. Kersters et al., “2-Keto-3-deoxy-D-gluconate,”Methods of Enzymology, 1975, pp. 99-101, vol. 41.
B. Nicolaus et al., “Production of 2-Keto-3-Deoxygluconate by Immobilized Cells of Sulfolobus Solfataricus,”Biotechnology Letters, 1986, pp. 497-500, vol. 8, No. 7.
Ando Tomoyuki
Fukuiri Yasushi
Ishibashi Hiroki
Komatsu Hironori
Miyake Hitoki
Buchanan & Ingersoll & Rooney PC
Gebreyesus Kagnew
Mitsui Chemicals Inc.
Prouty Rebecca E.
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