Glucocortioid mimetics, methods of making them,...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C548S361100

Reexamination Certificate

active

07622594

ABSTRACT:
Compounds of Formula (IA) and (IB)wherein R1, R2, R3, A, B, C, D, and E are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

REFERENCES:
patent: WO 00/32584 (2000-06-01), None
patent: WO 03/059899 (2003-07-01), None
patent: WO 03/082280 (2003-09-01), None
patent: WO 03/082787 (2003-09-01), None
patent: WO 2004/063163 (2004-07-01), None
patent: WO 2005/030213 (2005-04-01), None
Prodrug [online], [retrieved on Mar. 26, 2007]. Retrieved from the Internet, URL; http://en.wikipedia.org/wiki/Prodrug>.
Vippagunta, et al. Advanced Drug Delivery Reviews 48 (2001) 3-26.
Vippagunta, et al; Advanced Drug Delivery Reviews 48 (2001) 3-26.
Regan, John, et al; Advances Toward Dissociated Non-Steroidal Glucocorticoid Receptor Agonists, Annual Reports In Medicinal Chemistry, vol. 43, pp. 141-151, (2008).

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