Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2006-11-28
2006-11-28
Badio, Barbara P. (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C552S549000
Reexamination Certificate
active
07141559
ABSTRACT:
This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.
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patent: WO 99/44616 (1999-09-01), None
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Kramer, W. and Wess, G.: European Journal of Clinical Investigation, “Bile acid transport systems as pharmaceutical targets”, Vol. 26, p. 715-732 (1996).
Kramer, Werner, et al.: The Journal of Biological Chemistry, “Liver-specific Drug Targeting by Coupling to Bile Acids”, vol. 287, No. 26, p. 18598-18604 (1992).
Bishop Richard D.
Cink Russell Drew
Gates Bradley D.
Hagberg Lars T.
Jacobsen Peer B.
Badio Barbara P.
Galletta Elizabeth A.
Garabedian Todd E.
Karo Bio AB
Wiggin and Dana LLP
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