Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1989-06-15
1991-07-16
Page, Thurman
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 88, 424 89, 424 92, 514 54, 514885, 530817, A61K 3900, A61K 3912, A61K 3936, A61K 31715
Patent
active
050324012
ABSTRACT:
The invention describes a whole .beta.-glucan drug delivery vehicle that non-specifically enhances the immune response, and is safe for human use. A drug is incorporated into a whole .beta.-glucan microparticle, and the combination is administered to an individual. The .beta.-glucan vehicle allows sustained release of the drug component while simultaneously enhancing the effectiveness of the drug by boosting the individual's endogenous immune response.
REFERENCES:
patent: 4705780 (1987-11-01), Massot et al.
patent: 4739046 (1988-04-01), DiLuzio
patent: 4741872 (1988-05-01), DeLuca et al.
patent: 4761402 (1988-08-01), Williams et al.
patent: 4810646 (1989-03-01), jamas et al.
patent: 4857505 (1989-08-01), Arendt
Glucan-Enhanced Immunogenicity of Killed Erythrocylic Stages of Plasmodium Benghei, Holbrook et al., Infection and Immunity, 32, 542 (1981).
Glucan-Induced Enhancement of Host Resistance to Selected Infectious Diseases, Reynolds et al., Infection and Immunity, 30, 51 (1980).
S. Jamas et al., Biotech. and Bioeng., 28: 769-784 (1986).
Patent Abstracts of Japan, vol. 8, No. 270 (Dec., 1980), Masumoto.
S. Jamas et al., In: Industrial Polysaccharides: Genetic Engineering Structure/Property Relations and Appl., Elserier Science Publ. B.V., Amsterdam N. C., pp. 65-69 (1987).
J. K. Czop Pathology and Immunopathology Research, 5: 286-296 (1986).
J. A. Cook et al., Survey of Immunology Research, 2: 243-245 (1983).
W. Browder, Survey of Immunology Research, 2: 299-301 (1983).
M. L. Patchen, Survey Immunology Research, 2: 237-242 (1983).
J. A. Reynolds et al., Infection and Immunity, 20(1): 51-57 (1980).
T. W. Holbrook et al., Infection and Immunity, 32(2): 542-546 (1981).
J. L. Benach et al., Infection and Immunity, 35(3):947-951 (1982).
E. R. Sherwood et al., International Journal of Immunopharmacology, 9(3):261-267 (1987).
J. A. Cook et al., Infection and Immunity, 37(3): 1261-1269 (1982).
T. W. Holbrook et al., American Journal of Tropical Medical Hygiene, 32(1):51-53 (1983).
T. W. Holbrook et al., American Journal fo Tropical Medical Hygiene, 30(4):762-768 (1981).
J. A. Cook et al., Infection and Immunity, 40)3):1038-1043 (1983).
M. A. Chirigos et al., Cancer Research, 38:1085-1091 (1978).
Easson, Jr. D. Davidson
Jamas Spiros
Ostroff Gary R.
Alpha Beta Technology
Kishorl G. S.
Page Thurman
LandOfFree
Glucan drug delivery system and adjuvant does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Glucan drug delivery system and adjuvant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glucan drug delivery system and adjuvant will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-130290