Glucagon-like peptide-1 analogs

Details Glucagon-like peptide-1 analogs Glucagon-like peptide-1 analogs

2006-08-01

2006-08-01

Andres, Janet L. (Department: 1646)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

C530S308000, C514S002600, C435S004000, C435S007100

Reexamination Certificate

active

07084243

ABSTRACT:
Disclosed are glucagon-like peptide-1 (GLP-1) compounds with modifications at one or more of the following positions: 11, 12, 16, 22, 23, 24, 25, 27, 30, 33, 34, 35, 36, or 37. Methods of treating these GLP-1 compounds are also disclosed.

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Deacon, CF et al, : “Dipeptidyl Peptidase IV Resistant Analogues of Glucagon—Like Peptide-1 Which Have Extended Metabolic Stability and Improved Biological Activity,” Diabetologia, vol. 41, pp. 271-278, 1998 XP002202152 p. 276; figure 3; tables 1, 3.

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