Glucagon-like insulinotropic peptide analogs, compositions, and

Details Glucagon-like insulinotropic peptide analogs, compositions, and Glucagon-like insulinotropic peptide analogs, compositions, and

1994-10-18

1996-04-30

Warden, Jill

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530308, 530324, A61K 3800, A61K 3826, C07K 14605

Patent

active

055125492

ABSTRACT:
Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives are disclosed. The analogs include amino acid substitutions, amino and carboxyl terminal modifications, and C.sub.6 -C.sub.10 acylations. The claimed compounds stimulate the secretion or biosynthesis of insulin in poorly functioning beta cells and are therefore useful in treating Type II diabetics

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