Glucagon antagonists/inverse agonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S063000, C514S617000, C514S383000, C514S417000, C514S562000, C514S567000, C548S250000, C548S253000, C548S473000, C548S481000, C562S430000, C562S439000

Reexamination Certificate

active

06875760

ABSTRACT:
A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any glucagon-mediated conditions and diseases such as hyperglycemia, Type 1 diabetes, Type 2 diabetes and obesity.

REFERENCES:
patent: 4359474 (1982-11-01), Anderson et al.
patent: 4374130 (1983-02-01), Barcza
patent: 5776954 (1998-07-01), de Laszlo et al.
patent: 5837719 (1998-11-01), de Laszlo et al.
patent: 0 000 816 (1979-02-01), None
patent: 0 387 771 (1990-09-01), None
patent: 0 847 992 (1998-06-01), None
patent: 0 657 423 (1998-12-01), None
patent: WO 9414426 (1994-07-01), None
patent: WO 9509021 (1995-04-01), None
patent: WO 9610559 (1996-04-01), None
patent: WO 9716442 (1997-05-01), None
patent: WO 9804528 (1998-02-01), None
patent: WO 9821957 (1998-05-01), None
patent: WO 9822108 (1998-05-01), None
patent: WO 9822109 (1998-05-01), None
patent: WO 9824780 (1998-06-01), None
patent: WO 9824782 (1998-06-01), None
patent: WO 9850029 (1998-11-01), None
patent: WO 9850030 (1998-11-01), None
patent: 9901423 (1999-01-01), None
patent: WO 9901423 (1999-01-01), None
Brand et al., Diabetologia, vol. 37, pp. 985-993 (1994).
Brand et al., Am. J. Physiol., vol. 269 (Endocrinol. Metab. 32), pp. E469-E477 (1995).
Brand et al., Diabetes, vol. 45, pp. 1076-1083 (1996).
Jelinek et al., Science, vol. 259, pp. 1614-1616 (1993).
Unson et al., Peptides, vol. pp. 1171-1177 (1989).
Post et al., Biochemistry, vol. 90, pp. 1662-1666 (1993).
Madsen et al., J. Med. Chem., vol. 41, 41 pp. 5150-5157 (1998).
Collins et al., Bioorganic & Medicinal Chemistry Letters, vol. 2, pp. 915-918 (1992).
Azizeh et al., Bioorganic & Medicinal Chemistry Letters, vol. 5 pp. 15-30 (1998).
Tanaka et al., Bioorganic & Medicinal Chemistry Letters, vol. 6, pp. 15-30 (1998).
Unson et al., The Journal of Biological Chemistry, vol. 269, pp. 12548-12551 (1994).
Abstract of Japanese Patent JP 11302173.
Abstract of Brand et al., Diabetes, vol. 43, p. 172A (1994).
Abstract of Brand et al., Diabetes, vol. 44 Supplementary, p. 134A (1995).

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