Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-12-05
2006-12-05
Gupta, Anish (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S308000
Reexamination Certificate
active
07144863
ABSTRACT:
The present invention encompasses compositions wherein a GLP-1 compound is complexed with a basic polypeptide. The compositions provide a prolonged duration of action and can be administered by the pulmonary route.
REFERENCES:
patent: 6720407 (2004-04-01), Hughes et al.
patent: 0 619 322 (1994-10-01), None
Kim, et al., “Precipitation of Insulinotropin in the Presence of Protamine:Effect of Phenol and Zinc on the Isophane Ratio and the Insulinotropin Concentration in the Supernatant.” Pharmaceutical Research, 1995, vol. 12, No. 9, pp. 1284-1288.
Pridal, L. et al., “Absorption of Glucagon-Like Peptide-1 Can Be Protracted By Zinc or Protamine.” International Journal of Pharmaceutics, 1996, vol. 136; pp. 53-59.
DeFelippis Michael Rosario
Havel Henry Acken
Mace Kenneth F.
Ng Kingman
Sarin Virender Kumar
Cox Gregory A.
Eli Lilly and Company
Gupta Anish
Martinez Alejandro
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