Gliclazide nanosphere and manufacturing method therefor and...

Details Gliclazide nanosphere and manufacturing method therefor and... Gliclazide nanosphere and manufacturing method therefor and...

2011-03-08

2011-03-08

Vu, Jake M. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C264S005000, C977S906000

Reexamination Certificate

active

07901712

ABSTRACT:
An novel gliclazide nanosphere, the manufacturing method therefor and the application thereof are provided in the present application is provided. The gliclazide nanosphere is prepared by reacting the solid gliclazide with a polymeric matrix for improving the dissolution property and safety of gliclazide, and is benefit for immediately releasing dosage application in clinical therapy.

REFERENCES:
patent: 2006/0002998 (2006-01-01), Trehan et al.
Ozkan et al (Improvement of water solubility and in vitro dissolution rate of gliclazide by complexation with beta-cyclodextrin.Pharm Acta Helv. Apr. 2000;74(4):365-70).

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