Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2005-10-18
2005-10-18
Sitton, Jehanne (Department: 1634)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C536S023100, C536S024300
Reexamination Certificate
active
06956103
ABSTRACT:
Methods and compositions for preventing and treating glaucoma; and glaucoma diagnostics are disclosed.
REFERENCES:
patent: 5606043 (1997-02-01), Nguyen et al.
patent: 5789169 (1998-08-01), Nguyen et al.
patent: 5849879 (1998-12-01), Nguyen et al.
patent: 5854415 (1998-12-01), Nguyen et al.
patent: 5861497 (1999-01-01), Nguyen et al.
patent: 5885776 (1999-03-01), Stone et al.
patent: 5916778 (1999-06-01), Stone et al.
patent: 5925748 (1999-07-01), Stone et al.
patent: WO 96/14411 (1996-05-01), None
patent: WO 96/33287 (1996-10-01), None
patent: WO 98/20131 (1998-05-01), None
patent: WO 98/32850 (1998-07-01), None
patent: WO 99/16898 (1999-04-01), None
Alward et al; New England Journal of Medicine, vol. 338, pp 1022-1027, 1998.
Stone et al; Science, vol. 275; Jan. 31, 1997, pp 668-670.
Alward, Wallace L.M. et al., Clinical Failures Associated With Mutations in the Chromosome 1 Open-Angle Glaucoma Gene (GLCIA), New England Journal of Medecine, pp. 1022-1027 (1998).
“CHLC Report” (Newsletter), Cooperative Human Linkage Center, 1: 1-18 (May 1993).
Cotton, P., “Glaucoma Gene Mapped to Chromosome 1”, JAMA, 269(21):2715 (Jun. 2, 1993).
Ebert et al., “A Maloney MLV-Rat Somatotropin Fusion Gene Produces Biologically active Somatotropin in Transgenic Pig”Mol. Endo. 2(3): 277-283 (1988).
Eck, L. Stephen and Wilson M. James, “Gene-Based Therapy”, Goodman & Gilman's (The Pharmacological Basis of Therapeutics) Ninth Edition, Chapter 5, McGraw Hill Health Professions Division.
“Editorial: Genetic Associations of Glaucoma”, British Journal of Opthalmology 64: 225-226 (1980).
Escribano, J. et al., “Isolation and Characterization of Cell-Specific cDNA Clones from a Subtractive Library of the Ocular Ciliary Body of a Single Normal Human Donor: Transcription and Synthesis of Plasma Proteins”, J. Biochem., 118:921-931 (1995).
Francois, J. “Genetics and Primary Open-Angle Glaucoma”, Am. J. Ophthalmology 61:652-665, (1966).
Hammer, et al., “Genetic Engineer of Mammalian Embryos1,2,3”, J. Anim. Sci. 63:269-278 (1986).
Harris, D., “The Inheritance of Glaucoma: A Pedigree of Familial Glaucoma”, Am. J. Ophthalmology, 60:91-95 (1965).
Houdebine, Louis-Marie, “Production of Pharmaceutical Proteins From Transgenic Animals” Journal of Biotechnology 34: 269-287 (1994).
Johnson, A.T. et al., “Clinical Features and Linkage Analysis of a Family With Autosomal Dominant Juvenile Glaucoma”, Ophthalmology 100(4): 524-528 (Apr. 1993).
Kappel, et al., “Regulating Gene Expression in Transgenic Animals”, Current Opinion in Biotechnology 3 : 548-553 (1992).
Kass, M.A. et al., “Histocompatibility Antigens and Primary Open-Angle Glaucoma: A Reassessment” Arch Ophthalmology, 96: 2207-2208 (Dec. 1978).
Kolker, A. E., “Glaucoma Family Study: Ten Years Follow-up (Preliminary Report)”, Israel J. Med. Sci.,8 (8-9): 1357-1361 (Aug.-Sep. 1972).
Kubota, Ryo, et al., Genomic Organization of the Human Myocilin Gene (MYOC) Responsible for Primary Open Angle Glaucoma (GLCIA), Biochemical and Biophysical Research Communications 242(2) : 396-400 (Jan. 14, 1998).
Kubota, Ryo, et al., “A Novel Myosin-like Protein (Myocilin) Expressed in the Connecting Cilium of the Photoreceptor. Molecular Cloning Tissue Expression and Chromosomal Mapping”, Genomics 41: 360-369 (1997).
Leighton , D.A., “Survey of the First- Degree Relatives of Glaucoma Patients”, Trans. Ophthal. Soc. U.K., 96 : 28-32 (1976).
Martin, J.P. and E.C. Zorab, “Familial Glaucoma in Nine Generations of a South Hampshire Family”, Brit. J. Ophthalmology, pp. 536-542 (1974).
Miller, S.J.H. and G.D. Paterson, “Studies on Glaucoma Relatives”, Brit. J. Ophthalmology 46 : 513-522 (1962).
Moreadith R.W., and Radford N. B.,“Gene Targeting in Embryonic Stem Cells: The new Physiology and Metabolism”, J. Mol. Med., 75: 208-216 (1997).
Mullins, J. Linda, and Mullins, J. John., “Perspectives Series: Molecular Medicine in Genetically Engineered Animals”, J. Clin. Invest. 98(11) : S37-S40 (1996).
Nguyen, et al., Database Enrty HSU85257, (Mar. 2, 1997).
Nguyen, et al., “Cloning of Glucocorticoid (GC)-Induced Proteins in Him Cells: Verification of Progressive High-Dose Dependent cDNAs to Correlate With Effect on IOP.” Invest. Ophthalmol. Vis. Sci. 31 (4 abst.) 505, (1990).
Orita, M. et al., “Detection of Polymorphisms of Human DNA By Gel Electrophoresis as Single-Strand Conformation Polymorphisms”, Proc. Natl. Acad. Sci. USA. 86: 2766-2770 (Apr. 1989).
Orkin, et al., “Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy”.
Ortego, J. et al., “Cloning and Characterization of Subtracted cDNAs from a Human Ciliary Body Library Encoding TIGR, a Protein Involved in Juvenile Open Angle Glaucoma with Homology to Myosin and Olfactomedin”, FEBS Letters, 413 : 349-353 (1997).
Patridge et al., “Dexamethasone Induces Specific Proteins in Human Trabecular Meshwork Cells”, Investigativ Ophthalmology & Visual Science 30 (8) : 1843-1847 (Aug. 1989).
Perkins, E. S. , “ Family Studies of Glaucoma” Brit. J. Ophthalmol. 58 : 529-535 (1974).
Polansky, et al., “In Vitro Correlates of Glucocorticoid Effects on Intraoc,ular Pressure ”, G.K. Krieglstein (Ed): Glaucoma Update IV; Springer Vertag Berlin Heidelberg; pp. 20-29 (1991).
Polansky, et al., “The Ocular Effects of Prostaglandins and Other Elcosanoids”, Prog. Clin. Biol. Res. 312: 113-138 (1989).
Richards, J. E. et al., “Mapping of a Gene Autosomal Dominant Juvenile-Onset Open-Angle Glaucoma to Chromosome Iq”, Am. J. Hum. Genet., vol. 54 pp. 62-70 (1994).
Seamark R. F., “Progress and Emerging Problems in Livestock Transgenesis: a Summary Perpective”, Reprod. Fertil. Dev. 6 : 653-657 (1994).
Sheffield, V.C. et al., “Attachment of a 40-Base-Pair G+C-Rich Sequence (GC-clamp) to Genomic DNA Fragments by the Polymerase Chain Reaction Results in Improved Detection of Single-Base Changes”, Proc. Natl. Acad. Sci. USA 86 : 232-236 (Jan. 1989).
Sheffield, V.C., et al., “Genetic Linkage of Familial Open Angle Glaucoma to Chromosome 1q21-q31”, Nature Genetics 4: 47-50 (May 1993).
Stone, Edwin M., et al., “Identification of a Gene that Causes Primary Open Angle Glaucoma”, Science, 275 : 668-670 (Jan. 31, 1997).
Strojek, M. R. and Wagner E. T,. “The Use of Transgenic Animal Techniques for Livestock Improvement”, Genetic Engineering : Principles and Methods 10: 221-246 (1988), Plenum Press.
Sunden, Sara L. F. et al., “Fine Mapping of the Autosomal Dominant Juvenlle Open Angle Glaucoma (GLC1A) Region and Evaluation f Candidate Genes ”, Genome Res. 6: 862-869 (1996).
Wall, R. J., “Transgenic Livestock: Progress and Prospects for the Future”, Theriogenology 45: 57-68 (1996).
Wax, et al., “A Rationale for Gene Targeting in Glaucoma Therapy”, Journal of Ocular Pharmacology, 10 : 403-410 (1994).
Weatherhill, J. R. and Hart, C. T., “Familial Hypoplasia of the Iris Stroma Associated with Glaucoma ” Brit. J. Ophthal. 53 : 433-438 (1969).
Written Opinion dated Oct. 23, 1998.
Levitan et al. Textbook of Human Genetics, 3rd ed. Oxford University Press, pp. 32-33 (1988).
Alward Wallace L. M.
Fingert John
Sheffield Val C.
Stone Edwin M.
Needle & Rosenberg P.C.
Sitton Jehanne
The University of Iowa Research Foundation
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