Glaucoma formulations comprising an anionic, polysulfonic acid p

Details Glaucoma formulations comprising an anionic, polysulfonic acid p Glaucoma formulations comprising an anionic, polysulfonic acid p

1989-02-08

1992-03-03

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424400, 424486, A61K 900, A61K 914, A61F 200

Patent

active

050931261

ABSTRACT:
Disclosed are nonstinging, sustained release ophthalmic formulations. The formulations comprise a cationic drug, an acidic mucomimetic polymer and a polystyrene sulfonic acid polymer. In particular, formulations for the control of intraocular pressure and glaucoma are disclosed. Methods for use of the formulations are also disclosed.

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Heath et al., "Adsorption of B-Adrenoceptor Antagonists to Amberlite Resin", British Journal of Clinical Pharmacology, vol. 15, pp. 490-492 (1983).
Chemical Abstracts, vol. 98, 210936j (1983)-Heath et al.

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