Glass support coated with synthetic polymer for bioprocess

Chemistry: physical processes – Physical processes – Crystallization

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23915, 65 603, 204195B, 204195M, 204195P, 422 57, 424 1, 427 2, 435 7, 435180, 435181, 436531, 436512, G01N 3350, G01N 3354, G01N 3378, G01N 3358

Patent

active

043636349

ABSTRACT:
A new and useful process is disclosed for manufacturing a device for use in a bioprocess, comprising: (a) providing solid support means insoluble in water or organic solvent solutions; (b) coating said solid support means with water-based polymeric film means capable of applying one or more biomaterials; and (c) adsorbing or covalently bonding at least one functional biomaterial to said polymeric film means. The polymeric film means, for example, can be used to coat antigens, antibodies, haptens, enzymes, living bacteria, yeasts, etc. (i.e., biomaterials) to a glass (or other) support material, e.g., a glass tube, with surprising retention of the biomaterial's essential characteristic properties. The solid support means include but are not limited to those comprising glass, ceramics, metals, polymers and woods. The device of the invention is particularly useful in various immunoassays using a solid support for separation of phases.

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