Glass container internally coated with a silicone and having an

Details Glass container internally coated with a silicone and having an Glass container internally coated with a silicone and having an

1992-11-05

1994-08-09

Robinson, Ellis P.

Special receptacle or package

For body treatment article or material

428 347, 428429, 560121, 560122, 562503, 562504, A61B 1900

Patent

active

053357698

ABSTRACT:
A freeze-drying process which reduces loss of the freeze-dried product comprising adding a liquid solution comprising a solid product dissolved in a solvent to a glass container having its inside surface coated with a silicone material; subjecting the container with the liquid solution therein to acceptable operable freeze-drying conditions to remove the solvent and leave the solid product in the container in the form of a dense compact coherent solid; and sealing the container to maintain the solid product stable over a useful storage shelf life.
An article of manufacture comprising a sealed glass container having its inside surface coated with a silicone material and containing an in situ freeze-dried dense compact coherent solid product.

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National Formulary XIV, 1975, pp. 878-880.
Hartke, Mutschler, Publisher,"DAB 9 Commentary", vol. I, p. 353; Scientific Publishers GmbH, Stuttgart, Govi Publisher GmbH, Frankfurt, Aug., 1986.
H. Sucker, P. Fuchs, P. Speiser, "Pharmaceutical Technology", p. 762; George Thieme Publisher, Stuttgart Feb. 1978.

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