GIPs, a family of polypeptides with transcription factor...

Details GIPs, a family of polypeptides with transcription factor... GIPs, a family of polypeptides with transcription factor...

2006-11-09

2009-10-13

Mondesi, Robert B (Department: 1645)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S093200, C424S155100, C424S277100, C435S069700, C536S023700

Reexamination Certificate

active

07601349

ABSTRACT:
The present invention provides isolated GPBP-interacting 90 and 130 kDa polypeptides, and portions thereof (GIP90/130 polypeptides), antibodies to the GIP90/130 polypeptides, and pharmaceutical compositions thereof. The present invention also provides isolated GIP90/130 nucleic acid sequences, expression vectors comprising the nucleic acid sequences, and host cells transfected with the expression vectors. The invention further provides methods for detecting the GIP90/130 polypeptides or nucleic acid sequences, methods for inhibiting interactions between GPBP and GIP90/130 polypeptides, between pol k76 and GIP90/130 polypeptides or aggregation of GIP90/130 polypeptides, and methods for treating patients with autoimmune disorders or cancer.

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EMBL Entry Accession No. AF329092.
Genbank Entry Accession No. BC027860.

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