Gibberellins (including gibberellins A.sub.3 and A.sub.7) used i

Details Gibberellins (including gibberellins A.sub.3 and A.sub.7) used i Gibberellins (including gibberellins A.sub.3 and A.sub.7) used i

1998-11-09

2000-09-19

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514539, 560 35, 560116, 560117, A61K 31215, C07C22900, C07C 6974

Patent

active

061213179

ABSTRACT:
Compounds of formula (1), (Gibberellins), and their pharmaceutically acceptable derivatives to promote ulcer-healing, healing of surgical wounds or open fractures and treatment of bronchitis or thrombophlebitis in animals including humans or cultivation of skin cell lines in vitro ##STR1## wherein A is COOR, where R is hydrogen, unsubstituted or substituted C.sub.1-20 alkyl, allyl, aryl, arylalkyl, amidine, NR.sup.4 R.sup.5 or an unsaturated or saturated ring containing one or more hetero-atoms selected from the group consisting of nitrogen, oxygen and sulfur; R.sup.4 and R.sup.5 may or may not be the same, are hydrogen, or C.sub.1-20 alkyl, allyl, aryl, arylalkyl or an unsaturated or saturated ring containing one or more hetero-atoms selected from the group consisting of nitrogen and sulfur; B is hydrogen, hydroxyl, mercaptan, or halogen, or A and B together form a --CO--O-- linkage; R.sup.1 is hydrogen, hydroxyl, mercaptan, halogen, amino, azido, NR.sup.4 R.sup.5, unsubstituted or substituted C.sub.1-20 alkyl, allyl, aryl, arylalkyl, and R.sup.2 is methylene, or a divalent hetero-atom.

REFERENCES:
patent: 4424232 (1984-01-01), Parkinson
patent: 5487899 (1996-01-01), Davis
patent: 5580857 (1996-12-01), Oden
Milman, N., et al., "Lysine Prophylaxis in Recurrent Herpes Simplex Labialis: A Double-Blind, Controlled Crossover Study." Acta Derm Venereal (Stockh) (1980) 60 (1) 85-7.
Milman, N., et al. "Lysine Prophylaxis in Recurrent Labial Herpes Simplex." Ugeskr Laeger, May 5, 1980: 142 (19): 1202-3 (Eng. Abstr.).
Milman, N., et al. "Lysine Therapy of Recurrent Herpes Simplex Labialis." Ugeskr Laeger (Oct. 22, 1979) 141 (43): 2960-2 (Eng. Abstr.).
Spadoni, R., et al. "Lysine P-isobutyl-phenylpropinate in Articular and Extra-articular Osteoarthritis." Clin Ter. (Apr. 15, 1979) 89 (1) 75-86 (Eng. Abstr.).
Furber, M., et al. "New Synthetic Pathways from Gibberellins to Antheridiogens Isolated from the Fern Genus Anemia." Journal of Organic Chemistry, vol. 55, No. 15 (Jul. 1990) pp. 4860-4870.
Berkow, et al. "The Merck Manual." 16th Edition (1992) pp. 2401-2406.

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