Geranylgeranyl pyrophosphate synthases

Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se

Reexamination Certificate

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C435S006120, C435S069100, C435S468000, C435S419000, C435S252300, C435S320100, C435S183000, C530S370000, C536S023600, C800S278000

Reexamination Certificate

active

11032643

ABSTRACT:
This invention relates to an isolated nucleic acid fragment encoding a geranylgeranyl pyrophosphate synthase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the geranylgeranyl pyrophosphate synthase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the geranylgeranyl pyrophosphate synthase in a transformed host cell.

REFERENCES:
Kuntz, “Identification of a cDNA for the plastid-located geranylgeranyl pyrophosphate eynthase from Capsicum annuum: correlative increase in enzyme activity and transcript level during fruit ripening,”Plant J.,Jan. 1992;2(1):25-34.
Lai et al. “Guemao, a Drosophila bristle locus, encodes geranylgeranyl pyrophosphate Synthase,”Genetics,Jun. 1998;149(2):1051-61.
Zhu et al., “Garanylgeranyl pyrophosphate synthase encoded by the newly isolated gene GGPS6 fromArabidopsis thalianais localized in mitochondria,”Plant Mol Biol.,Oct. 1997;35(3):331-41.
Adams et al., “Complementary DNA sequencing: expressed sequence tags and human gename project,”Science,Jun. 21, 1991;252(5013):1651-6.
NCBI General Identifier No. 558925, geranylgeranyl pyrophosphate Synthase gl|558925|gb|AAA86688.1|[558925].
Aitken et al. “A cDNA encoding geranytgeranyl pyrophosphate synthase from white lupin,”Plant Physiol,Jun. 1995;108(2):837-8.
NCBI General Identifier No. 2464899 geranylgeranyl pyrophosphate synthase[Arabidopsis thaliana] gi|2464899|emb|CAB16803.1|[2464899].
NCBI General Identifier No. 462174 sp|P34802|GGPP—ARATH[462174].
Scolnik et al., “Nucleotide sequence of an Arabidopsis cDNA for geranylgeranyl pyrophosphate synthase,”Plant Physiol.,Apr. 1994;104(4):1469-70.
NCBI General Identifier No. 1419758 geranylgeranyl pyrophosphate synthase [Slnapls alba] gi|1419756|emb|CAA67330.1|[1419756].
Bank et al., “Chloroplast import of four carotenoid biosynthetic enzymes in vitro reveals differential fates prior to membrane binding and oligomeric assembly,”Eur J Biochem,1997 247;942-950.
NCBI General Identifier No. 5042456 putative geranylgeranyl pyrophosphate synthase [Oryza aativa (|aponica cultivar-group)] gi|5042456|gb|AAD38295.1|AC00789—21[5042458].
NCBI General Identifier No. 1063276 geranylgeranyl pyrophosphate synthase [Catheranthus roseus] gi|1063276|emb|CAA63486.1|[1063276].
Bantignies et al., “Nucleotide sequence of aCatharanthus roseusgeranylgeranyl pyrophosphate synthase gene,”Plant Physiol,1996, vol. 110, p. 336.
NCBI General Identifier No. 735880 geranylgeranyl pyrophosphate synthase-related protein gl|735880|gb|AAA81879.1|[735880].
Scolnick et al., “Nucleotide sequence of lycoperic cyclase (GenBank L40176) fromArabidopsis(PGR95-019)m”Plant Physiol.,1995, vol. 108, No. 3, p. 1343.
NCBI General Identifier No. 4467133 geranylgeranyl pyrophosphate synthase-related protein [Arabidopsis thaliana] gl|4467133|emb|CAB37502.1|[4467133].
Bartley et al., “A tomato gene expressed during fruit ripening encodes an enzyme of the carotenoid biosynthesis pathway,”J Biol Chem.,Mar. 16, 1992;267(8):5036-9.
Bork, “Powers and pitfalls in sequence analysis: the 70% hurdle,”Genome Res,Apr. 2000;10(4):398-400.

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