Geranylgeranyl pyrophosphate synthases

Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se

Reexamination Certificate

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Details

C435S006120, C435S069100, C435S468000, C435S419000, C435S252300, C435S320100, C530S370000, C536S023600, C800S278000

Reexamination Certificate

active

06855868

ABSTRACT:
This invention relates to an isolated nucleic acid fragment encoding a geranylgeranyl pyrophosphate synthase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the geranylgeranyl pyrophosphate synthase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the geranylgeranyl pyrophosphate synthase in a transformed host cell.

REFERENCES:
Kuntz, “Identification of a cDNA for the plastid-located geranylgeranyl pyrophosphate synthase from Capsicum annuum: correlative increase in enzyme activity and transcript level during fruit ripening,”Plant J., 1992 Jan.;2(1):25-34.
Lai et al. “Guemao, a Drosophila bristle locus, encodes geranylgeranyl pyrophosphate Synthase,”Genetics, 1998 Jun.; 149(2):1051-81.
Zhu et al., “Geranylgeranyl pyropphosphate synthase encoded by the newly isolated gene GGPS6 from Arabidopsis thallana is localized in mitochondria,”Plant Mol Biol., 1997 Oct.;35(3):331-41.
Adams et al., “Complementary DNA sequencing: expressed sequence tags and human genome project,”Science, Jun. 21, 1991;252(5013):1651-6.
NCBI General Identifier No. 558925, geranylgeranyl pyrophosphate Synthase gl|558925|gb|AAA86688.1|[558925].
Aitken et al. “A cDNA encoding geranylgeranyl pyrophosphate synthase from white lupin,”Plant Physiol, 1995 Jun.;108(2):837-8.
NCBI General Identifier No. 2464899 geranylgeranyl pyrophosphate synthase [Arabidopsis thaliana] gi|2464899|amb|CAB16803.1|[2464899].
NCBI General Idenitifier No. 462174 sp|P34802|GGPP-ARATH[462174].
Scolnik et al., “Nucleotide sequence of an Arabidopsis cDNA for geranylgeranyl pyrophosphate synthase,”Plant Physiol., 1994 Apr;104(4):1469-70.
NCBI General Identifier No. 1419758 geranylgeranyl pyrophosphate synthase [Sinapis alba] gl|1419758|emb|CAA67330.1|[1419758].
Bonk et al., “Chloroplast import of four carotenoid biosynthetic enzymes in vitro reveals differential fates prior to membrane binding and oligomeric assembly,”Eur J Biochem, 1997 247;942-950.
NCBI General Identifier No. 5042458 putative geranylgeranyl pyrophosphate synthase [Oryza sativa (laponica cultivar-group)] gi|5042458|gb|AAD38295.1|AC007789-21[5042458].
NCBI General Identifier No. 1063276 geranylgeranyl pyrophosphate synthase [Catharanthus roseus] gi|1063276|emb|CAA63486.1|[1063276].
Bantignies et al., “Nucleotide sequences of aCatharanthus roseusgeranylgeranyl pyrophosphate synthase gene,”Plant Physiol, 1996, vol. 110, p. 336.
NCBI General Identifier No. 735880 geranylgeranyl pyrophosphate synthase-related protein gi|735880|gb|AAA81879.1|[735880].
Scolnick et al., “Nucleotide sequence of lycopene cyclase (GenBank L40176) fromArabidopsis(PGR95-019)m”Plant Physiol., 1995, vol. 108, No. 3, p. 1343.
NCBI General Identifier No. 4467133 geranylgeranyl pyrophosphate synthase-related protein [Arabidopsis thellana] gi|4467133|emb|CAB37502.1|[4467133].
Bartley et al., “A tomato gene expressed during fruit ripening encodes an enzyme of the carotenoid biosynthesis pathway,”J Biol Chem., Mar. 16, 1992;267(8):5036-9.
Bork, “Powers and pitfalls in sequence analysis: the 70% hurdle,”Genome Res. 2000 Apr;10(4):398-400.

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