Genus-specific oligomers of Borrelia and methods of using same

Details Genus-specific oligomers of Borrelia and methods of using same Genus-specific oligomers of Borrelia and methods of using same

1991-04-15

1994-02-01

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 184, 536 286, 536 243, 536 2433, 925 70, 925 72, 925 77, C12Q 168, C12P 1934, C07H 1700, C07H 504

Patent

active

052831752

ABSTRACT:
The subject invention provides DNA oligomers complementary to portions of the flagellin gene of Borrelia burgdorferi which can be used to detect the organism, as well as other Borrelia species, in a sample. PCR technology can be used to amplify the portion of the flagellin gene which is then detected using a biotinylated probe provided by the subject invention.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4800159 (1989-01-01), Mullis et al.
patent: 4888276 (1989-12-01), Shelburne
patent: 4965188 (1990-10-01), Mullis et al.
D. Dodge and T. J. White, Abstract D-137, Abstracts of 90th Annual Meeting of the American Society for Microbiology, p. 103 (1990).
D. C. Malloy et al., Abstract D-138, Abstracts of 90th Annual Meeting of the American Society for Microbiology, p. 103 (1990).
D. Wise and T. Weaver, Abstract D-139, Abstracts of 90th Annual Meeting of the American Society for Microbiology, p. 103 (1990).
S. L. Nielsen et al., Molecular and Cellular Probes 4: 73-79 (1990).
D. H. Persing et al., J. Clin. Micro. 28: 566-572 (1990).
Schwan et al. J. Clin Microb. 27(8):1734 (1989).
Goodman et al. Clin. Res. 37(2):429A (1989).
Gassmann et al. Nuc. Acid Res. 17(9):3590 (1989).
Rosa et al. J. Inf. disease 160(6) 1018 (1989).
Malloy et al. J. Clin. Microb. 28(6):1089 (1990).
Schwan & Barbour in "Lyme disease and Related Disorders", Ann. N.Y. Acad. Sc. 539:419 (1988).
Barbour, A., Ann. Int. Med. 110(7) 501 (1989).
Chen et al. FEMS Microb Lett. 57:19 (1989).
Persing et al. Science 249:1420-1423 (1990).
Wallich et al., Infec. & Immun. 58(6):1711-1719 (1990).

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