Genus-specific listeria antigen identified by monoclonal antibod

Details Genus-specific listeria antigen identified by monoclonal antibod Genus-specific listeria antigen identified by monoclonal antibod

1987-08-10

1990-08-21

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435810, 436548, 530350, 530387, 530806, 530809, 530825, G01N 33569, G01N 33577

Patent

active

049505890

ABSTRACT:
Antigens characteristic of all species of Listeria except L. denitrificans comprising proteins found in Listeria heat extracts, the major antigen having a molecular weight of from about 30 to about 38KD and comprising three immunogenically different epitopes and others comprising proteins having a molecular weight range of approximately 17KD to the major antigen and comprising an epitope immunoreactive with antibodies that are also reactive with one of the three epitopes on the 30 to about 38KD protein. The invention also comprises mouse monoclonal antibodies specifically reactive with the identified epitopes on these antigens.

REFERENCES:
Farber et al., Journ. Food Protect., 50, 479-484, 1987.
Khan et al., Zbl. Bakt. Hyg., I. Abt. Orig. A., 239, 62-69, 1977.
Seeliger et al., In Sneath et al. (Eds), Bergy's Manual of systematic Bacteriology, vol. 2, 6th Ed., Williams & Wilkins, 1984, pp. 1235-1237.
Sevier et al., Clinical Chem., 27, 1797-1806, 1981.

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