Gentisic acid salts as radiographic scanning agent stabilizers

Details Gentisic acid salts as radiographic scanning agent stabilizers Gentisic acid salts as radiographic scanning agent stabilizers

1980-11-03

1985-02-05

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2604385R, 424 11, C07F 722

Patent

active

044977441

ABSTRACT:
Stable compositions, useful as technetium-99m-based scintigraphic agents, comprise gentisic acid or a pharmaceutically-acceptable salt or ester thereof in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (.sup.99m TcO.sub.4.sup.-) solution. The compositions are especially useful in combination with a phosphate or phosphonate material which carries the radionuclide to bone, thus providing a skeletal imaging agent.

REFERENCES:
patent: 3673157 (1972-06-01), Price et al.
Fenton et al., Inorganica Chimica Acta, 4, 235-243, (1970).
Honnick et al., Inorganic Chemistry, 17, 501-504, (1978).
Chemical Abstracts, vol. 54, 19259a, (1960).
Chemical Abstracts, vol. 79: 35670b, (1973).

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