Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-12-20
2008-10-21
Lucas, Zachariah (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023100, C536S024310, C536S024320
Reexamination Certificate
active
07439020
ABSTRACT:
The present invention provides methods of predicting a pre-disposition of HBV-infected individuals to develop hepatacellular carcinoma (HCC).
REFERENCES:
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Kao J-H et al. “Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers”. Gastroenterology. Feb. 2003;124(2):327-34.
Cougot D. et al “HBV induced carcinogenesis.” J. Clinical Virology 34 Suppl. (2005) S75-S78.
Gao, Jidong et al.; “Close Relation between Hepatocellular Carcinoma and HBV Infection in North China”; 2004,Chin. J. Hepatobiliary Surg., vol. 10, No. 6, 9 pages.
Lin, Xu et al.; “Structural Analysis of 22 Full-Length Hepatitis B Virus Genomes Isolated from Patients with Hepatocellular Carcinoma”; 2004,Chin. J. Oncol., vol. 26, No. 4, 12 pages.
Yue, Feng-e et al.; “Relations Between Hepatocellular Carcinoma and HBV Infection”; 2001,China J. Cancer Prev Treat., vol. 8, No. 6, 8 pages.
Zhu, Rong et al.; “Progress in Study on Relations between Hepatitis B Virus X Protein and Hepatocellular Carcinoma”; 2004, Foreign Medical Sciences Epidemiology Lemology, vol. 31, No. 4, 10 pages.
Blackberg, Jonas et al.; “Mutations Within the Hepatitus B Virus Genome Among Chronic Hepatitus B Patients With Hepatocellular Carcinoma”; 2003,Journal of Medical Virology, vol. 71, pp. 18-23.
Chan, H L-Y et al.; “Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma”; 2004,Gut, vol. 53, pp. 1494-1498.
Bartholomeusz Angeline
Chan Lik Yuen
Lee Kin Hong
Leung Kwong Sak
Leung Wai Yee Nancy
Lucas Zachariah
Peng Bo
The Chinese University of Hong Kong
The Hospital Authority
Townsend and Townsend / and Crew LLP
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