Surgery: splint – brace – or bandage – Bandage structure – Support covering
Patent
1998-07-25
1999-11-09
Lewis, Aaron J.
Surgery: splint, brace, or bandage
Bandage structure
Support covering
128844, 128842, 602 60, 435240, A61F 1300
Patent
active
059804777
ABSTRACT:
This invention relates to the use of water-soluble zinc salts as anti-viral agents in genital lubricants (such as condom lubricants or stand-alone gels), to reduce the risk of infection by sexually transmitted viruses. Such zinc-containing anti-viral lubricants can be spread on the shaft of the penis or inside the vagina before sexual intercourse, or applied in other suitable manners that causes the lubricant fluid to be coated on one or more genital surfaces during intercourse. These lubricants also can be sealed in watertight packages containing lubricated condoms, or packaged and sold as "stand-alone" lubricants in watertight containers without condoms. Preferred lubricants contain a water-soluble lubricating agent, such as glycerin or polyethylene glycol, and a suitable zinc salt, and water, to promote ionization of the salt and release of zinc ions (Zn.sup.++). Such lubricants may also contain a thickening or suspending agent, such as a cellulose derivative, a natural gum compound, or a hydrophilic polymer, to provide a gel. Suitable zinc salts include water-soluble organic salts having relatively low molecular weights (including zinc acetate, butyrate, gluconate, glycerate, glycolate, lactate, propionate, etc.). Highly ionizing inorganic salts, such as zinc chloride or sulfate, can also be used in some formulations. Several preferred salts were tested by human volunteers, during intercourse, and did not cause any detectable irritation.
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Chvapil, M., et al., "Reaction of vaginal tissue of rabbit and of cheek pouch of hamster to inserted collagen sponges treated with either zinc or copper," Am. J. Obstet. Gynecol. 130: 63-70 (1978).
Chvapil, M., et al., "Ultrastructure of the vaginal tissue of rabbits treated with collagen sponge alone and medicated with zinc and copper salts and copper wire," Fertility and Sterility 30: 461-469 (1978).
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Golden Marc
Hart Kelvin
Kelly Patrick
Kelly Patrick D.
Lewis Aaron J.
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