Genital lubricants containing zinc as an anti-viral agent

Details Genital lubricants containing zinc as an anti-viral agent Genital lubricants containing zinc as an anti-viral agent

1994-12-22

1997-02-04

Azruru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

424401, 424407, 424614, 514774, 514777, 514781, 514785, 514786, 514886, 514931, 514934, 514944, 514966, 514967, 514968, 514969, A61K 740, A61K 31325, A61K 3330, A01N 5502

Patent

active

055995519

ABSTRACT:
This invention relates to an article of manufacture comprising an aqueous gel containing a selected zinc salt contained within a deformable plastic-walled tubular container, for convenient and consistent use as a topical genital lubricant during acts of sexual intercourse. The zinc salt must be organic, water-soluble, and have substantial dissociation rates to release divalent zinc ions. Suitable zinc salts include zinc acetate, zinc propionate, zinc butyrate, zinc formate, zinc gluconate, zinc glycerate, zinc glycolate, and zinc lactate. The gel must also contain a thickening agent (such as chemically treated cellulose) and a lubricating agent (such as glycerin), and it must be free of heparin, dextran sulfate, or any other anti-coagulant or other component which poses a substantial risk of adverse effects if the lubricant is used frequently and repeatedly over a period of months or years. The zinc-containing lubricants described herein can reduce the risk that a previously uninfected person will become infected by genital herpes viruses, and possibly by HIV, hepatitis, or papilloma viruses or other sexually transmitted pathogens, during or after intercourse with an infected partner.

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