Surgery – Male reproductory tract shields or birth control devices
Patent
1995-06-05
1998-07-28
Brown, Michael A.
Surgery
Male reproductory tract shields or birth control devices
A61F 602
Patent
active
057850542
ABSTRACT:
This invention relates to an article of manufacture including a genital lubricant containing a selected non-irritating, water-soluble zinc salt at an anti-viral concentration, within a package that is provided with a label indicating that the lubricant is effective as an anti-viral agent against at least one type of sexually transmitted virus (such as genital herpes viruses, human immunodeficiency viruses, hepatitis viruses, or papilloma viruses). One such lubricant includes a lubricant gel in a plastic-walled tubular package, for use with or without a condom; another such lubricant includes a condom lubricant, coated on a condom and sealed along with the condom inside a disposable plastic pouch. The zinc salt must be water-soluble and have substantial dissociation rates to release divalent zinc ions, and the lubricant must not cause genital irritation or other adverse effects, even if used repeatedly over a period of months or years. The zinc-containing lubricants described herein can reduce the risk that a previously uninfected person will become infected by sexually transmitted viruses, and the labelling information will help promote efficacy and slow the spread of incurable viruses.
REFERENCES:
patent: 4407818 (1983-10-01), Lienolle et al.
patent: 4465666 (1984-08-01), Lukas et al.
patent: 4548950 (1985-10-01), Baxendale et al.
patent: 4604404 (1986-08-01), Munson et al.
patent: 4684490 (1987-08-01), Tuller
patent: 4869270 (1989-09-01), Ueno et al.
patent: 4910803 (1990-03-01), Cukier
patent: 4919966 (1990-04-01), Shlenker
patent: 4992259 (1991-02-01), Schiraldi et al.
See attached pp. 2 & 3.
Brawner, T.A., et al, "A Combined Chemical-Physical Treatment for Herpes Simplex Lesions in Guinea Pigs," Arch. Dermatol. Res. 265: 71-77 (1979).
Brody, I., "Topical treatment of recurrent herpes simplex . . . zinc sulphate solution," Brit. J. Dermatol. 104: 191-194 (1981).
Chvapil et al, "Reaction of vaginal tissue of rabbit and of cheek pouch of hamster to inserted collagen sponges treated with either zinc or copper," Am. J. Obstet. Gynecol. 130: 63-70 (1978).
Eby, G.A., and W.W. Halcomb, "Use of topical zinc to prevent recurrent herpes simplex infection: review of literature and suggested protocols," Medical Hypotheses 17: 157-165 (1985).
Fahim, M.S. and Brawner, T.A., "Treatment of Genital Herpes Simplex Virus in Male Patients," Arch. Andrology 4: 79-85 (1980).
Fahim, M. et al, "New Treatment for Herpes Simplex Virus Type 2. Part 2--Female Patients,"J. Medicine 11(2&3): 143-167 (1980).
Fahim, M., et al, "New Treatment for Herpes Simplex Virus Type 2 Patients," J. Medicine 9(3): 245-264 (1978).
Fitzherbert, J.C., "Genital Herpes and Zinc," Med. J. Australia, May 5, 1979, p. 399.
Fridlender, B., et al, "Selective inhibition of herpes simplex virus type 1 DNA polymerase by zinc ions," Virology 84: 551-554 (1978).
Gordon, Y.J., et al, "Irreversible inhibition of herpes simplex virus replication in BSC-1 cells by zinc ions," Antimicrob. Agents Chemother. 8: 377-380 (1975).
Gupta, P., and Rapp, F., "Effect of zinc ions on synthesis of herpes simplex virus type 2-induced polypeptides," Pro. Soc. Exp. Biol. Med. 152: 455-458 (1979).
Jones, R., "Genital Herpes and Zinc," Med. J. Australia, Apr. 7, 1979, p. 286.
Merck Index, pp. 1598-1601 11th edition, (1989).
Sergio, W., "Zinc Salts that may be Effective Against the AIDS Virus HIV," Medical Hypotheses 26(4): 251-253 (1988).
Shlomai, J., et al, "Effect of zinc ions on the synthesis of herpes simplex virus DNA in infected BSC-1 cells," Virology 66: 330-335 (1975).
Tennican, P., et al, "Topical Zinc in the Treatment of Mice Infected Intravaginally with Herpes Genitalis Virus," Proc. Soc. Exp. Biol. Med. 164: 593-597 (1980).
Tennican, P.O., et al, "The Diverse Effects of Topical and Systemic Administration of Zinc on the Virulence of Herpes Simplex Genitalis," Life Sciences 24: 1877-1884 (1979).
Williams, W.L., "New antifertility agents active in the rabbit vaginal contraception method," Contraception 22: 659-672 (1980).
Wahba, A., "Topical Application of Zinc Solutions: A New Treatment for Herpes Simplex Infections of the Skin?" Acta Derm. Venerol. (Stockholm) 60: 175-177 (1980).
Brown Michael A.
Kelly Patrick D.
LandOfFree
Genital lubricant with zinc salt, labelled as anti-viral agent does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Genital lubricant with zinc salt, labelled as anti-viral agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Genital lubricant with zinc salt, labelled as anti-viral agent will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-15259