Genetically modified yeast strain

Details Genetically modified yeast strain Genetically modified yeast strain

2011-05-03

2011-05-03

Joike, Michele K (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

C435S254100

Reexamination Certificate

active

07935514

ABSTRACT:
A polyploid transformed yeast cell comprising a deleted or disrupted GDH1 gene encoding an NADPH-dependent glutamate dehydrogenase. The polyploid yeast cell shows increased production of ethanol and reduced production of glycerol when compared with a control polyploid yeast cell.

REFERENCES:
patent: 7018829 (2006-03-01), Nielsen et al.
Zeyl et al. Experimental studies on ploidy evolution in yeast. FEMS Microbiol Lett. Apr 15, 2004;233(2):187-92.
Grotakjaer T. et al., “Comparative Metabolic Network Analysis of Two Xylose Fermenting Recombinant Saccharomyces Cerevisiae”, Metab Eng., 2005, pp. 437-444, vol. 7-Iusses 5-6, Elsevier Inc.
Moreira Dos Santos M. et al., “Aerobic Physiology of Redox Engineered Saccharomyces Cerevisiae Strains Modified in the Ammonium Assimilation for Increased NADPH Availability”, FEMS Yeast Research, 2003, pp. 59-68, vol. 4 Issue 1, Blackwell Publishing Ltd.
Roca C. et al., “Metabolic Engineering of Ammonium Assimilation in Xylose-Fementing Saccharomyces Cerevisiae improves ethanol production”, Applied and Environmental Microbiology, Aug. 2003, pp. 4732-4736, vol. 69 No. 8, American Society for Microbiology.
Nissen T.L. et al., “Optimization of Ethanol Production in Saccharomyces Cerevisiae by Metabolic engineering of the ammonium assimilation”, Metabolic Engineering, Jan. 2000, pp. 69-77, vol. 2 Issue 1, Academic Press.
Whitehouse, “Towards an Understanding of the Mechanism of Heredity”, Edward Arnold Ltd., London, 1965, pp. 327 and 330.
Wilson et al., “Cytology”, Reinhold Publishing Corporation, 1961, pp. 174-179.
Swanson, “Cytology and Cytogenetics”, MacMillan & Co Ltd., 1963, p. 177.
“Saccharomyces Genome Database FAQ”, http://www.yeastgenome.org/SGD-FAQ.html, last updated on website on Mar. 18, 2004.
Hieter et al., “Genetics: Polyploidy—More Is More or Less”, Science Magazine, vol. 285, No. 5425, Jul. 9, 1999, pp. 210-211.
Canadian Patent Application 2,641,003 Office Action dated Feb. 28, 2011.

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