Genetically modified pseudomonas strains with enhanced biocontro

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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424 932, 424 934, 424 9347, 435 691, 4351723, 435183, 435476, 435477, 800 205, C12N 120, C12N 1500, A01N 6300, C12P 2106

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active

059553480

ABSTRACT:
Strains of Pseudomonas have been genetically engineered to have enhanced biocontrol properties. The strains of the invention are particularly effective against plant pathogenic fungi such as species of Rhizoctonia and Pythium, because the strains produce enhanced amounts of antifungal metabolites such as pyrrolnitrin that are active against these fungal pathogens. Both the genetically modified biocontrol strains and the antifungal metabolites can be used as active agents for biocontrol compositions.

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Hrabak et al., "The lemA Gene Required for Pathogenicity of Pseudomonas syringae pv. Syringae on Bean Is a Member of a Family of Two-Component Regulators", J. of Bacteriology, 174(9): 3011-3020 (1992).
Laville et al., "Global control in Pseudomonas fluorescens mediating antibiotic synthesis and suppression of black root rot of tobacco", Proc. Natl. Acad. Sci., 39: 1562-1566 (1992).
Liao et al., "Molecular Characterization of Two Gene Loci Required for Production of the Key Pathogenicity Factor Pectate Lyase in Pseudomonas viridiflava", Molecular Plant-Microbe Interactions, 7(3): 391-400 (1994).
Pierson et al., "Cloning and Heterologous Expression of the Phenazine Biosynthetic Locus from Pseudomonas aureofaciens 30-84", Molecular Plant-Microbe Interactions, 5(4): 330-339 (1992).

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