Genetically modified cells and methods for converting...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Reexamination Certificate

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C435S252330, C435S007100

Reexamination Certificate

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10829897

ABSTRACT:
RecombinantEscherichia colihost cells that comprise recombinant DNA expression vectors that drive expression of methylmalonyl CoA mutase fromPropionibacterium shermaniiorStreptomyces cinnamonensisas well asPropionibacterium shermaniiepimerase can produce S-methylmalonyl CoA, a required substrate for the production of polyketides by most modular polyketide synthases not present in wild-typeE. colihost cells.

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